Evidence map›Paper›PMID 31890893›Full record

ArticleInternational journal of herbal medicine

A traditional Chinese medicine compound (Jian Er) for presbycusis in a mouse model: Reduction of apoptosis and protection of cochlear sensorineural cells and hearing.

Yi Xuan, Dalian Ding, Weijun Xuan, Liyi Huang, Junbo Tang, Yulong Wei, Sizhong Chen, Michael R Hamblin

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of herbal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Application of New Materials in Auditory Disease Treatment.Frontiers in cellular neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yi XuanSchool of Engineering, Tufts University, Medford, MA, USA.
Dalian DingCenter for Hearing Deafness, the State University of New York at Buffalo, Buffalo, NY, USA.
Weijun XuanDepartment of Otorhinolaryngology, Head and Neck Surgery, First Clinical Medical College and Hospital, Guangxi University of Chinese Medicine,Nanning, China.
Liyi HuangWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
Junbo TangDepartment of Otorhinolaryngology, Head and Neck Surgery, First Clinical Medical College and Hospital, Guangxi University of Chinese Medicine, Nanning, China.
Yulong WeiDepartment of Pharmaceutical Manufacturing, Ruikang Clinical Medical College, Guangxi University of Chinese Medicine, Nanning, China.
Sizhong ChenDepartment of Otorhinolaryngology, Head and Neck Surgery, First Clinical Medical College and Hospital, Guangxi University of Chinese Medicine, Nanning, China.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
Guangxi University of Chinese Medicine · CNMassachusetts General Hospital · USRuikang Affiliated Hospital of Guangxi Medical University · CNTufts University · US

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

Age-related hearing loss (AHL) or presbycusis is steadily increasing due to the overall aging of the Chinese population. Traditional Chinese medicine (TCM) has long been used to prevent and treat deafness, but its effectiveness and mechanism of action are still uncertain. The present study tested a TCM preparation called "Jian Er" in a mouse model of prebycusis.

Indexed as

auditory brainstem responseC57BL/6J micepresbycusistraditional Chinese medicine

Identifiers

PMID31890893
PMCPMC6936738
OpenAlexW3005594001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.