ArticleLaryngoscope investigative otolaryngology2019
Radiation exposure alters airway deformability and bony structure displacement during laryngoscopy.
Article in Laryngoscope investigative otolaryngology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundPrior therapeutic radiation exposure in the setting of head and neck malignancies is associated with difficult airway instrumentation. We sought to characterize the anatomic changes that produce this phenotype. STUDY
designRetrospective review.
methodsFive individuals with prior radiation therapy to the upper aerodigestive tract (previously irradiated) and 10 with no prior history of therapeutic radiation exposure (nonirradiated) were enrolled. Computed tomography images obtained before and during laryngoscope insertion ("uninstrumented" and "instrumented", respectively) were used to reconstruct three-dimensional representations of the pharyngeal airway, hyoid, and mandible.
resultsIn the instrumented state, pharyngeal airway volumes were significantly greater in nonirradiated subjects relative to previously irradiated subjects (
conclusionIndividuals with prior therapeutic radiation exposure to the upper aerodigestive tract differ from nonirradiated subjects with respect to airway deformation and bony structure translation during laryngoscopy. LEVEL OF EVIDENCE: 4.
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