ReviewLaryngoscope investigative otolaryngology2019
Reconstruction of segmental mandibular defects: Current procedures and perspectives.
Review in Laryngoscope investigative otolaryngology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Trial
- Two-piece magnet-retained silicone lip prosthesis in a mandibulectomy patient with lower lip defect following oncologic resection: A clinical case report.Journal of Indian Prosthodontic Society · 2026Article
- SA/HA double-network hydrogel combined with PVDF electret membrane enhances osteogenic differentiation of DPSCs and promotes mandibular bone defect repair.Regenerative therapy · 2026Article
- Comparison of non-transport disc and conventional distraction osteogenesis for mandibular segmental defect reconstruction.Journal of orthopaedic surgery and research · 2026Article
- Anterolateral Thigh Flap and Bone Plate for Mandibular Reconstruction in Patients over 55 Undergoing Ablative Oral Surgery: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Apelin-13 enhances BMSCs osteogenic differentiation and bone regeneration under hypoxia via upregulation of Ibsp.Stem cell research & therapy · 2026Article
- Superior Biomechanics of Patient-Specific Mandibular Reconstruction Plate: A Validated Computational-Experimental Framework.Annals of biomedical engineering · 2026Article
- Adjustable Single-Osteotomy Fibular Free Flap for Anterior Mandibular Defects in Irradiated Head and Neck Cancers-A Case Series.Journal of clinical medicine · 2025Article
- Comparison of the Outcome of Free Iliac Bone Graft and Vascularized Iliac Bone Graft in Reconstruction of Mandibular Defects: A Systematic Review.Journal of maxillofacial and oral surgery · 2024Review
- Evaluation of stiffness-matched, 3D-printed, NiTi mandibular graft fixation in an ovine model.Biomedical engineering online · 2024Article
- MicroRNA-29c-tetrahedral framework nucleic acids: Towards osteogenic differentiation of mesenchymal stem cells and bone regeneration in critical-sized calvarial defects.Cell proliferation · 2024Article
- Bioengineering from the laboratory to clinical translation in oral and maxillofacial reconstruction.The Saudi dental journal · 2024Review
- Reconstruction of Segmental Mandibular Defects with Double-Barrel Fibula Flap and Osseo-Integrated Implants: A Systematic Review.Journal of clinical medicine · 2024Review
- Perioperative pain management after scapular tip free flap harvesting for head and neck reconstruction using mini-catheters to inject the local anesthetic.Oral and maxillofacial surgery · 2024Article
- The Reconstruction of Mandible Defects in War Injuries: Systematic Review and Meta-Analysis.Craniomaxillofacial trauma & reconstruction · 2024Review
- Trends and Patterns in Mandible Bone Cancer Research: An Updated Comprehensive Bibliometric Review : Prevalence of Supernumerary Teeth in Patients with Cleft lip and Palate.Galen medical journal · 2024Article
- Titanium Alloy Implants with Lattice Structures for Mandibular Reconstruction.Materials (Basel, Switzerland) · 2023Review
- Hydrogels for Oral Tissue Engineering: Challenges and Opportunities.Molecules (Basel, Switzerland) · 2023Review
- Advanced Hydrogel systems for mandibular reconstruction.Bioactive materials · 2023Review
- β-TCP from 3D-printed composite scaffolds acts as an effective phosphate source during osteogenic differentiation of human mesenchymal stromal cells.Frontiers in cell and developmental biology · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe reconstruction of segmental mandibular defects remains a challenge for the reconstructive surgeon, from both a functional and an esthetic point of view.
methodsThis clinical review examines the different techniques currently in use for mandibular reconstruction as related to a range of etiologies, including the different bone donor sites, the alternatives to free flaps (FFs), as well as the contribution of computer-assisted surgery. Recent progress and the perspectives in bone tissue engineering (BTE) are also discussed.
resultsOsseous FF allows reliable and satisfying outcomes. However, locoregional flap, distraction osteogenesis, or even induced membrane techniques are other potential options in less favorable cases. Obtaining an engineered bone with satisfactory mechanical properties and sufficient vascular supply requires further investigations.
conclusionsOsseous FF procedure remains the gold standard for segmental mandible reconstruction. BTE strategies offer promising alternatives.
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Registered trials
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