Evidence map›Paper›PMID 31890461›Full record

ArticleCurrent hepatology reports2019

Testing for Hepatitis C in Pregnancy: the Time has Come for Routine Rather than Risk-based.

Tatyana Kushner, Catherine A Chappell, Arthur Y Kim

Abstract read
In one paragraph

Article in Current hepatology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Viral hepatitis in pregnancy.Journal of viral hepatitis · 2022
    Review
  4. Prospective cohort study of children exposed to hepatitis C virus through a pregnancy screening program.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tatyana KushnerDivision of Liver Diseases, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1123, New York, NY, 10029.
Catherine A ChappellDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15206.
Arthur Y KimDivision of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street Cox 6, Boston, MA 02114.

Funding

Building Research Careers in Women's HealthK12HD043441 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2002 to 2023
$10.1M
A Phase 1 Pharmacokinetic Trial of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination in Pregnant Women with Chronic Hepatitis C Virus InfectionR21HD089457 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI CHAPPELL, CATHERINE · 2016 to 2017
$451k
NICHD NIH HHS K12 HD043441NICHD NIH HHS R21 HD089457
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to discuss the reasons for HCV testing during pregnancy and to review what is known about antiviral treatment during pregnancy. RECENT

findingsHepatitis C virus affects over 3 million persons in the United States and is one of the leading infectious causes of death. While HCV is most commonly transmitted via parenteral exposures, thus affecting people who inject drugs, it is also transmitted from mother-to-child. Due to an expanding opioid crisis, an increasing number of women of childbearing age are now infected, resulting in transmission to infants. Risk-based screening has never been proven effective and thus universal screening of pregnant women for HCV infection has been recommended. SUMMARY: Obstetricians may play a key role in the U.S. by implementing universal testing for HCV in pregnant women, thereby enhancing the health of mothers and identifying children at risk.

Indexed as

antiviral treatmenthepatitis C virusperinatal transmissionpregnancytesting

Identifiers

PMID31890461
PMCPMC6936758

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.