Evidence map›Paper›PMID 31890454›Full record

ArticleIntractable & rare diseases research2019

Malignant transformation of hepatic adenoma complicated by rupture and hemorrhage: An extremely rare clinical entity.

Rishi Philip Mathew, Florin Manolea, Safwat Girgis, Vimal Patel, Gavin Low

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Intractable & rare diseases research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rishi Philip MathewDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, Edmonton, Canada.
Florin ManoleaDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, Edmonton, Canada.
Safwat GirgisDepartment of Laboratory Medicine & Pathology, Faculty of Medicine and Dentistry, University of Alberta Hospital, Edmonton, Canada.
Vimal PatelDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, Edmonton, Canada.
Gavin LowDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, Edmonton, Canada.
Alberta Hospital Edmonton · CAUniversity of Alberta Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic adenomas (HAs) are rare benign tumors of the liver and comprise 2% of all liver tumors with an annual incidence of 3-4/100,000 per year in Europe and North America. These tumors may be clinically silent or present with abdominal pain. Although rare, the most important complications associated with this tumor is haemorrhage and malignant transformation to hepatocellular carcinoma. The reported risk of malignant transformation is believed to be 4.2%. We present an extremely rare case report of a young woman on the oral contraceptive pill (OCP) with malignant transformation of a hepatic adenoma complicated additionally by tumor rupture and intraperitoneal bleed. This article therefore highlights the need to carefully evaluate any liver lesion in a young female on the OCP to be a possible adenoma and if confirmed to be so, to consider the potential risks associated with it as well as the need for follow-up imaging in order to avoid life threatening complications.

Indexed as

hemorrhageHepatic adenomahepatocellular carcinomainflammatory adenomamalignant transformationoral contraceptive pill

Identifiers

PMID31890454
PMCPMC6929599
OpenAlexW3000663425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.