Evidence map›Paper›PMID 31890269›Full record

ArticleBiomaterials research2019

Optimization of silver nanoparticle synthesis by chemical reduction and evaluation of its antimicrobial and toxic activity.

Catalina Quintero-Quiroz, Natalia Acevedo, Jenniffer Zapata-Giraldo, Luz E Botero, Julián Quintero, Diana Zárate-Triviño, Jorge Saldarriaga, Vera Z Pérez

Open access · goldAbstract read
In one paragraph

Article in Biomaterials research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 213 citations in OpenAlex.

  1. Greener synthesis of silver nanoparticles fromFrontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Catalina Quintero-Quiroz1Centro de Bioingeniería, Grupo de investigaciones en Bioingeniería, Universidad Pontificia Bolivariana, circular 1 No. 73-76, Medellín, 050031 Colombia.ORCID 0000-0001-9682-5530
Natalia Acevedo1Centro de Bioingeniería, Grupo de investigaciones en Bioingeniería, Universidad Pontificia Bolivariana, circular 1 No. 73-76, Medellín, 050031 Colombia.
Jenniffer Zapata-Giraldo2Grupo de Investigación de Biología de Sistemas,Universidad Pontificia Bolivariana, Cl 78B No. 72A-109, Medellín, 050031 Colombia.
Luz E Botero2Grupo de Investigación de Biología de Sistemas,Universidad Pontificia Bolivariana, Cl 78B No. 72A-109, Medellín, 050031 Colombia.
Julián Quintero3Universidad de Antioquia, Cl.67 No. 53-108, Medellín, 050010 Colombia.
Diana Zárate-Triviño4Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, Ave. Pedro de Alba S/N Ciudad Universitaria San Nicolás de los Garza, Monterrey, 64450 México.
Jorge Saldarriaga5Grupo de Investigación Sobre Nuevos Materiales, Universidad Pontificia Bolivariana, Cq.1 No. 70-01, Medellín, 050031 Colombia.
Vera Z Pérez1Centro de Bioingeniería, Grupo de investigaciones en Bioingeniería, Universidad Pontificia Bolivariana, circular 1 No. 73-76, Medellín, 050031 Colombia.
Universidad Pontificia Bolivariana · COUniversidad Autónoma de Nuevo León · MXUniversidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemical reduction has become an accessible and useful alternative to obtain silver nanoparticles (AgNPs). However, its toxicity capacity depends on multiple variables that generate differences in the ability to inhibit the growth of microorganisms. Thus, optimazing parameters for the synthesis of AgNPs can increase its antimicrobial capacity by improving its physical-chemical properties.

methodsIn this study a Face Centered Central Composite Design (FCCCD) was carried out with four parameters:

resultsIt was found that the four factors studied were significant for the response variables, and a significant model (p < 0.05) was obtained for each variable. The optimal conditions were 8 for pH and 0.01 M, 0.0 6M, 0.01 M for the concentration of TSC,

conclusionsIt was found that the factors studied were significant for the variable responses and the optimization process used was effective to improve the antimicrobial activity of the AgNPs.

Indexed as

Antimicrobial activityCytotoxicityDesign of experimentsResponse surface methodologySilver nanoparticles

Identifiers

PMID31890269
PMCPMC6921438
OpenAlexW2995700575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.