ArticlePilot and feasibility studies2019
Cognitive-behavioural therapy for the management of inflammatory bowel disease-fatigue: a feasibility randomised controlled trial.
Article in Pilot and feasibility studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025Pooled it
- Efficacy of different psychological interventions for the treatment of inflammatory bowel disease: a systematic review and network meta-analysis.Frontiers in medicine · 2025Pooled it
- Effectiveness and safety of non-pharmacological therapies for the treatment of inflammatory bowel disease: a network meta-analysis.Frontiers in medicine · 2025Pooled it
- Interventions for fatigue in inflammatory bowel disease.The Cochrane database of systematic reviews · 2020Pooled it
- The Future of Telehealth-Based Psychological and Mind-Body Interventions for People With Inflammatory Bowel Disease: A Systematic Review.Journal of digestive diseasesPooled it
- Feasibility, Acceptability, and Preliminary Efficacy of Acceptance Commitment Therapy for Adults Living With Inflammatory Bowel Disease and Distress.Inflammatory bowel diseases · 2024Trial
- Fatigue in inflammatory bowel disease: Mechanisms, assessment, and management strategies.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Specific Depressive Symptoms are Associated with Subtypes of Fatigue in Inflammatory Bowel Disease.Journal of clinical psychology in medical settings · 2026Article
- A Qualitative Template Analysis to Understand Patient and Practitioner Perspectives on a Psychological Intervention for Fatigue in Inflammatory Bowel Disease.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis.BMJ medicine · 2026Article
- Exploring the Mediating Role of Self-Efficacy in the Relationship Between Caregiver Contribution and Resilience in Inflammatory Bowel Disease.Behavioral sciences (Basel, Switzerland) · 2025Article
- Fatigue in inflammatory bowel disease: Prevalence, risk factors, assessment, outcomes, and management.World journal of gastrointestinal pathophysiology · 2025Review
- Feasibility, acceptability, and exploratory outcomes of a virtual cognitive behavioural therapy-based group intervention for persistent fatigue in endometriosis: The Managing Fatigue in Endometriosis (MEND) programme.British journal of health psychology · 2025Article
- Management of Fatigue in Inflammatory Bowel Disease: A Narrative Review.International journal of general medicine · 2025Review
- Unraveling the fatigue puzzle: insights into the pathogenesis and management of IBD-related fatigue including the role of the gut-brain axis.Frontiers in medicine · 2024Review
- Self-Worth Beliefs Predict Willingness to Engage in Psychotherapy for Fatigue in Inflammatory Bowel Disease.Digestive diseases and sciences · 2022Article
- The Experience of Self-conscious Emotions in Inflammatory Bowel Disease: A Thematic Analysis.Journal of clinical psychology in medical settings · 2022Article
- A Novel Digital Self-management Intervention for Symptoms of Fatigue, Pain, and Urgency in Inflammatory Bowel Disease: Describing the Process of Development.JMIR formative research · 2022Article
- Management of Crohn's stricture: medical, endoscopic and surgical therapies.Frontline gastroenterology · 2022Article
- Are we addressing the top 10 research priorities in IBD?Frontline gastroenterology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFatigue is the third most prevalent symptom for patients with inflammatory bowel disease (IBD), yet optimal strategies for its management are unclear. Treatment protocols for fatigue in other conditions have been based on cognitive-behavioural models. Targeting cognitions, emotions and behaviour related to fatigue through cognitive-behavioural therapy (CBT) may be a viable option to improve fatigue and quality of life (QoL) in IBD.
methodsThis single centre, two-arm, feasibility randomised controlled trial (RCT) aimed to assess the feasibility and initial estimates of potential efficacy of a CBT intervention for the management of IBD-fatigue. Feasibility, acceptability and initial estimates of potential efficacy outcomes were collected through self-report measures and semi-structured interviews. Participants were recruited from one tertiary referral centre. Intervention Group 1 received a CBT manual for fatigue, one 60-min and seven 30-min telephone sessions with a therapist over 8-weeks. Control Group 2 received a fatigue information sheet without therapist support. A nested qualitative study evaluated patients' and therapists' experiences, and IBD-healthcare professionals' (HCPs) perceptions of the intervention.
resultsEighty-nine participants were assessed for eligibility. Of these, 31 of the 70 eligible participants consented to participate (recruitment rate of 44%). Of the 15 participants randomised to the intervention group, 13 (87%) started it and 10 (77% of those who started) completed all 8 sessions. Follow-up questionnaires were completed by 22 (71%) participants at 3 months, 14 (45%) at 6 months and 12 (39%) at 12 months' follow-up. The intervention was acceptable to participants and feasible for therapists to deliver. HCPs reported that the intervention would be applicable, but time, finance and training constraints limit its implementation. Initial estimates of potential efficacy with complete case analysis showed a reduction in fatigue and an increase in QoL at 3, 6 and 12 months post-randomisation.
conclusionsA full-scale effectiveness RCT testing CBT for IBD-fatigue is feasible and is potentially worthwhile with some changes to the protocol. However, given the small numbers, further pilot work is warranted before a full-scale RCT.
trial registrationRegistration Trial ISRCTN 17917944, Registered 2 September 2016.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.