Evidence map›Paper›PMID 31890079›Full record

ArticleJournal of microbiology & biology education2019

A Scalable CURE Using a CRISPR/Cas9 Fluorescent Protein Knock-In Strategy in

Eric Hastie, Ryan Sellers, Bruno Valan, David R Sherwood

Open access · goldAbstract read
In one paragraph

Article in Journal of microbiology & biology education, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. AJournal of microbiology & biology education · 2026
    Article
  2. Article
  3. Article
  4. WormTagDB: A Systematic Survey of Endogenously Tagged Proteins inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eric HastieDepartment of Biology, Duke University, Durham, NC 27708.
Ryan SellersDepartment of Biology, Duke University, Durham, NC 27708.
Bruno ValanDepartment of Biology, Duke University, Durham, NC 27708.
David R SherwoodDepartment of Biology, Duke University, Durham, NC 27708.
Duke University · US

Funding

Understanding how cells invade through basement membrane in vivoR35GM118049 · NIGMS · DUKE UNIVERSITY · PI David R Sherwood · 2016 to 2026
$6.8M
NIGMS NIH HHS R35 GM118049
6 · The paper itself

Abstract

Genome editing with CRISPR/Cas9 technology has advanced from the lab bench to clinical application with multiple trials underway. This article introduces a course-based undergraduate experience (CURE) combining CRISPR/Cas9 genome editing (using a modified two-plasmid system) and the animal model

Identifiers

PMID31890079
PMCPMC6914349
OpenAlexW2994808706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.