Evidence map›Paper›PMID 31890020›Full record

ReviewBiotechnology for biofuels2019

Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas.

Tomomi Takeuchi, Christoph Benning

Open access · goldAbstract readReview
In one paragraph

Review in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Uncoupling growth and division inISME communications · 2025
    Article
  9. Article
  10. Article
  11. N-Acetyl-L-glutamate Kinase ofInternational journal of molecular sciences · 2023
    Article
  12. Review
  13. Article
  14. The Role of GmSnRK1-GmNodH Module in Regulating Soybean Nodulation Capacity.International journal of molecular sciences · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tomomi Takeuchi1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 USA.
Christoph Benning1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 USA.ORCID 0000-0001-8585-3667
Michigan State University · US

Funding

Plant Biotechnology for Health and SustainabilityT32GM110523 · NIGMS · MICHIGAN STATE UNIVERSITY · PI LAST, ROBERT LOUIS · 2014 to 2023
$2.2M
NIGMS NIH HHS T32 GM110523
6 · The paper itself

Abstract

Microalgae hold great promises as sustainable cellular factories for the production of alternative fuels, feeds, and biopharmaceuticals for human health. While the biorefinery approach for fuels along with the coproduction of high-value compounds with industrial, therapeutic, or nutraceutical applications have the potential to make algal biofuels more economically viable, a number of challenges continue to hamper algal production systems at all levels. One such hurdle includes the metabolic trade-off often observed between the increased yields of desired products, such as triacylglycerols (TAG), and the growth of an organism. Initial genetic engineering strategies to improve lipid productivity in microalgae, which focused on overproducing the enzymes involved in fatty acid and TAG biosynthesis or inactivating competing carbon (C) metabolism, have seen some successes albeit at the cost of often greatly reduced biomass. Emergent approaches that aim at modifying the dynamics of entire metabolic pathways by engineering of pertinent transcription factors or signaling networks appear to have successfully achieved a balance between growth and neutral lipid accumulation. However, the biological knowledge of key signaling networks and molecular components linking these two processes is still incomplete in photosynthetic eukaryotes, making it difficult to optimize metabolic engineering strategies for microalgae. Here, we focus on nitrogen (N) starvation of the model green microalga,

Indexed as

BiofuelBiomassCell cycleChlamydomonasDREAM complexNitrogen deprivationQuiescenceSnRK/CKINTORTriacylglycerols

Identifiers

PMID31890020
PMCPMC6927116
OpenAlexW2995157772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.