ArticleSaudi journal of biological sciences2020
Screening for obesity in the offspring of first-cousin consanguineous couples: A Phase-I study in Saudi Arabia.
Article in Saudi journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Article
- The Antioxidant Potential of the Mediterranean Diet as a Predictor of Weight Loss after a Very Low-Calorie Ketogenic Diet (VLCKD) in Women with Overweight and Obesity.Antioxidants (Basel, Switzerland) · 2022Article
- Independent case-control study inSaudi journal of biological sciences · 2022Article
- Screening of fluoride analysis as a biochemical parameter in the orthodontic treatment using fixed appliances.Saudi journal of biological sciences · 2022Article
- Omentin as an Independent Predictor of Metabolic Syndrome and Obesity Among Adolescents in Northeast China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Screening of biochemical parameters in the orthodontic treatment with the fixed appliances: A follow-up study.Saudi journal of biological sciences · 2021Article
- Real time polymerase chain reaction analysis in the patients treated with fixed appliances after the orthodontic treatment: A follow-up study.Saudi journal of biological sciences · 2021Article
- Family History, Consanguinity and Other Risk Factors Affecting the Prevalence of Prediabetes and Undiagnosed Diabetes Mellitus in Overweight and Obese Yemeni Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Influence of Parental Physical Activity and Screen Time on the BMI of Adult Offspring in a Saudi Population.Healthcare (Basel, Switzerland) · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Consanguineous or cousin marriages are very common in Saudi Arabia. However, owing to limited studies and insufficient knowledge about genetic diseases/disorders, many couples are unaware of the increased health risks for their offspring. Among the inherited and complex diseases from parents' consanguinity, obesity is common; therefore, we examined the prevalence of obesity in the offspring of first-cousin consanguineous couples in Saudi Arabia. In this questionnaire-based study, 657 individuals (mean age = 18.7 ± 10.2 years; age range = 2-65 years) who were residing in Riyadh, Saudi Arabia participated. Among them, almost 90% were native Saudis. Participants mean body mass index (BMI) was 24.5 ± 9.1 kg/m2. Sex- stratified demographic details confirmed a significant association between age and BMI (p < .001). We confirmed that adolescents and adults were more prone to develop obesity. Adults and non-Saudi participants were three times more likely to develop obesity if they had first-cousin consanguineous parents than those who did not. Of the 30% of participants who were obese, 100 will be selected for Phase II, in which we plan to perform exome sequencing.
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