Evidence map›Paper›PMID 31889795›Full record

ArticleSaudi journal of biological sciences2019

Analgesic effect of the midazolam-induced anesthesia in different doses on the patients after the thoracoscopic resection of lung cancer.

Lixia Zhang, Gang Wang, Jianhui Gan, Zhongci Dou, Liying Bai

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lixia ZhangDepartment of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.
Gang WangDepartment of Anesthesiology, Tianjin First Central Hospital, Tianjin 300190, China.
Jianhui GanDepartment of Anesthesiology, The Affiliated Tangshan People's Hospital of North China University of Science and Technology, Tangshan 063000, China.
Zhongci DouDepartment of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.
Liying BaiDepartment of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.
First Affiliated Hospital of Zhengzhou University · CNNorth China University of Science and Technology · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo elaborate the analgesic efficiency of midazolam-induced anesthesia in different doses on the patients following the thoracoscopic resection of lung cancer.

methodsNinety patients undergoing thoracoscopic resection of lung cancer between August 2017 and July 2018 were randomized in the observation group (n = 45) and the control group (n = 45). Patients in observation group underwent the anesthesia induced by 0.1 mg/kg midazolam, while for the control group, the dose was adjusted to 0.05 mg/kg. Then, we compared the levels of inflammatory factors, SaO

resultsAt the postoperative 48 h, patients in the observation group had lower levels of inflammatory factors when comparing with their counterparts in the control group [IL-6, IL-8, IL-1β and TNF-α: (58.44 ± 3.22) μg/L, (2.04 ± 0.26) μg/L, (2.98 ± 0.44) μg/L, (5.33 ± 0.77) μg/L

conclusionFor patients of thoracoscopic resection of lung cancer, midazolam-induced anesthesia (0.1 mg/kg) performs better than 0.5 mg/kg in inhibiting the inflammatory responses, with significant reduction in the dose of anesthetics, thereby stabilizing the status of patients in perioperative period and mitigating the postoperative pains. Thus, it is potential candidate.

Indexed as

AnalgesiaAnesthesiaBronchial lung cancerInduction doseMidazolam

Identifiers

PMID31889795
PMCPMC6923446
OpenAlexW2972895137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.