ArticleNMR in biomedicine2020
Magnetic resonance elastography-derived stiffness of the kidneys and its correlation with water perfusion.
Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Virtual MR elastography with diffusion-weighted imaging to evaluate chronic kidney disease fibrosis and dysfunction.Radiology advances · 2026Article
- Kidney Elastography in Adult Nephrology: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Factors influencing renal shear wave elastography: effects of probe orientation, respiration, corticomedullary differentiation, and hydration.Journal of ultrasonography · 2026Article
- The evolving field of nephrology: what comes next? A report from the European Renal Association Scientific Advisory Board.Clinical kidney journal · 2026Review
- Association of In Vivo Kidney Stiffness Measured by Multifrequency MR Elastography and Long-Term Renal Function in Transplant Recipients and Living Donors.Journal of magnetic resonance imaging : JMRI · 2025Article
- Advancements in the non-invasive diagnosis of renal fibrosis.Frontiers in medicine · 2025Review
- Magnetic resonance elastography resolving all gross anatomical segments of the kidney during controlled hydration.Frontiers in physiology · 2024Article
- Advances in imaging techniques to assess kidney fibrosis.Renal failure · 2023Review
- Multiparametric Magnetic Resonance Imaging of the Kidneys: Effects of Regional, Side, and Hydration Variations on Functional Quantifications.Journal of magnetic resonance imaging : JMRI · 2023Article
- Measurement of renal congestion and compliance following intravenous fluid administration using shear wave elastography.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023Article
- Effects of kidney perfusion on renal stiffness and tissue fluidity measured with tomoelastography in an MRI-compatibleFrontiers in bioengineering and biotechnology · 2023Article
- Importance of Confounding Factors in the Evaluation of Surrogate Measures for Kidney Transplant Fibrosis.Kidney360 · 2022Article
- Multiparametric quantitative renal MRI in children and young adults: comparison between healthy individuals and patients with chronic kidney disease.Abdominal radiology (New York) · 2022Article
- MR Elastography of the Abdomen: Experimental Protocols.Methods in molecular biology (Clifton, N.J.) · 2021Article
- MR Elastography of the Abdomen: Basic Concepts.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Ultrasound Shear Wave Elastography and Transient Optical Coherence Elastography: Side-by-Side Comparison of Repeatability and Accuracy.IEEE open journal of engineering in medicine and biology · 2021Article
- Cerebral Ultrasound Time-Harmonic Elastography Reveals Softening of the Human Brain Due to Dehydration.Frontiers in physiology · 2020Article
- Magnetic resonance elastography of liver.Magnetic resonance imaging clinics of North America · 2014Review
- A Case of Shear Wave Velocity Reflecting the Disease Activity in Glomerulonephritis.Journal of medical ultrasoundArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Stiffness plays an important role in diagnosing renal fibrosis. However, kidney stiffness is altered by perfusion changes in many kidney diseases. Therefore, the aim of the current study is to determine the correlation of kidney stiffness with water intake. We hypothesize that kidney stiffness will increase with 1 L of water intake due to increased water perfusion to the kidneys. Additionally, stiffness of the kidneys will correlate with apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values before and after water intake. A 3 T MRI scanner was used to perform magnetic resonance elastography and diffusion tensor imaging of the kidneys on 24 healthy subjects (age range: 22-66 years) before and after water intake of 1 L. A 3D T1-weighted bladder scan was also performed to measure bladder volume before and after water intake. A paired t-test was performed to evaluate the effect of water intake on the stiffness of kidneys, in addition to bladder volume. A Spearman correlation test was performed to determine the association between stiffness, bladder volume, ADC and FA values of both kidneys before and after water intake. The results show a significant increase in stiffness in different regions of the kidney (ie, percentage increase ranged from 3.6% to 7.5%) and bladder volume after water intake (all P < 0.05). A moderate significant negative correlation was observed between change in kidney stiffness and bladder volume (concordance correlation coefficient = -0.468, P < 0.05). No significant correlation was observed between stiffness and ADC or FA values before and after water intake in both kidneys (P > 0.05). Water intake caused a significant increase in the stiffness of the kidneys. The negative correlation between the change in kidney stiffness and bladder volume, before and after water intake, indicates higher perfusion pressure in the kidneys, leading to increased stiffness.
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