Evidence map›Paper›PMID 31889178›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2020

A combined strategy of feature selection and machine learning to identify predictors of prediabetes.

Kushan De Silva, Daniel Jönsson, Ryan T Demmer

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Machine Learning-Based Prediction of Binge Drinking among Adults in the United State: Analysis of the 2022 Health Information National Trends Survey.Proceedings of the 2024 9th International Conference on Mathematics and Artificial Intelligence · 2024
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  13. Prediction of Prednisolone Dose Correction Using Machine Learning.Journal of healthcare informatics research · 2023
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  14. Article
  15. Machine Learning in Nutrition Research.Advances in nutrition (Bethesda, Md.) · 2022
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  19. Machine learning for diabetes clinical decision support: a review.Advances in computational intelligence · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kushan De SilvaDepartment of Clinical Sciences, Faculty of Medicine, Lund University, Lund,Sweden.
Daniel JönssonDepartment of Periodontology, Malmö University, Malmö and Swedish Dental Service of Skane, Lund, Sweden.
Ryan T DemmerDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify predictors of prediabetes using feature selection and machine learning on a nationally representative sample of the US population. MATERIALS AND

methodsWe analyzed n = 6346 men and women enrolled in the National Health and Nutrition Examination Survey 2013-2014. Prediabetes was defined using American Diabetes Association guidelines. The sample was randomly partitioned to training (n = 3174) and internal validation (n = 3172) sets. Feature selection algorithms were run on training data containing 156 preselected exposure variables. Four machine learning algorithms were applied on 46 exposure variables in original and resampled training datasets built using 4 resampling methods. Predictive models were tested on internal validation data (n = 3172) and external validation data (n = 3000) prepared from National Health and Nutrition Examination Survey 2011-2012. Model performance was evaluated using area under the receiver operating characteristic curve (AUROC). Predictors were assessed by odds ratios in logistic models and variable importance in others. The Centers for Disease Control (CDC) prediabetes screening tool was the benchmark to compare model performance.

resultsPrediabetes prevalence was 23.43%. The CDC prediabetes screening tool produced 64.40% AUROC. Seven optimal (≥ 70% AUROC) models identified 25 predictors including 4 potentially novel associations; 20 by both logistic and other nonlinear/ensemble models and 5 solely by the latter. All optimal models outperformed the CDC prediabetes screening tool (P < 0.05). DISCUSSION: Combined use of feature selection and machine learning increased predictive performance outperforming the recommended screening tool. A range of predictors of prediabetes was identified.

conclusionThis work demonstrated the value of combining feature selection with machine learning to identify a wide range of predictors that could enhance prediabetes prediction and clinical decision-making.

Indexed as

Machine LearningAdultAlgorithmsArea Under CurveFemaleHumansMaleMiddle AgedModels, TheoreticalNutrition SurveysPrediabetic StatePrevalenceRisk FactorsROC CurveSocioeconomic Factorsfeature selectionmachine learningNHANESprediabetespredictors

Identifiers

PMID31889178
PMCPMC7647289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.