Evidence map›Paper›PMID 31889144›Full record

ArticleScientific reports2019

Pralatrexate in patients with recurrent or refractory peripheral T-cell lymphomas: a multicenter retrospective analysis.

Jung Yong Hong, Dok Hyun Yoon, Sang Eun Yoon, Seok Jin Kim, Ho Sup Lee, Hyeon-Seok Eom, Hye Won Lee, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon and 8 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Jung Yong HongDepartment of Oncology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-1363-9332
Dok Hyun YoonDepartment of Oncology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea.
Sang Eun YoonDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Seok Jin KimDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Ho Sup LeeDepartment of Internal Medicine, Kosin University Gospel Hospital, Busan, Republic of Korea.
Hyeon-Seok EomCenter for Hematologic Malignancies, National Cancer Center, Goyang, Republic of Korea.
Hye Won LeeCenter for Hematologic Malignancies, National Cancer Center, Goyang, Republic of Korea.
Dong-Yeop ShinDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Youngil KohDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Sung-Soo YoonDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Jae-Cheol JoDepartment of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Jin Seok KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Soo-Jeong KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Su-Hee ChoDivision of Hematology-Oncology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Republic of Korea.
Won-Sik LeeDepartment of Internal Medicine, Inje University College of Medicine, Inje University Busan Paik Hospital, Gaegumdong, Busanjingu, Busan, Republic of Korea.
Jong-Ho WonDivision of Hematology & Oncology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Won Seog KimDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. wskimsmc@skku.edu.
Cheolwon SuhDepartment of Oncology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea. csuh@amc.seoul.kr.
Asan Medical Center · KRSamsung Medical Center · KRYonsei University · KRKosin University Gospel Hospital · KRSeoul National University Hospital · KRInje University Busan Paik Hospital · KRNational Cancer Center · KRPusan National University Yangsan Hospital · KRSoonchunhyang University Hospital Seoul · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of non-Hodgkin's lymphomas with poor clinical outcomes. Pralatrexate showed efficacy and safety in recurrent or refractory PTCLs. The purpose or this study was to investigate the efficacy and safety of pralatrexate in relapsed or refractory PTCLs in real-world practice. This was an observational, multicenter, retrospective analysis. Between December 2012 and December 2016, a total of 38 patients with relapsed or refractory PTCLs were treated with pralatrexate at 10 tertiary hospitals in Korea. Patients received an intravenous infusion of pralatrexate at a dose of 30 mg/m

Indexed as

AgedAged, 80 and overAminopterinAntineoplastic AgentsDisease ManagementDrug Resistance, NeoplasmFemaleHumansLymphoma, T-Cell, PeripheralMaleMiddle AgedNeoplasm StagingPrognosisRecurrenceRetreatmentRetrospective Studies10-propargyl-10-deazaaminopterinAminopterinAntineoplastic Agents

Identifiers

PMID31889144
PMCPMC6937326
OpenAlexW2997897178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.