ArticleScientific reports2019
Layered material platform for surface plasmon resonance biosensing.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 98 citations in OpenAlex.
- Cooperative Host-Guest Complexation in Densely Assembled Host Structures on Surfaces Revealed at the Single-Molecular Level.Journal of the American Chemical Society · 2026Article
- Double-Sided Illumination Grating-Coupled Surface Plasmon Resonance Sensors Using Direct Optical Discs.Materials (Basel, Switzerland) · 2026Article
- Highly sensitive and label-free detection of SARS-CoV-2 proteins via surface plasmon resonance using biofunctionalization with 1 nm thick carbon nanomembranes.Scientific reports · 2025Article
- Towards a Rational Design of Biosensors: Engineering Covalently Grafted Interfacial Adlayers as a Testbed Platform for Electrochemical Detection of Epinephrine.Molecules (Basel, Switzerland) · 2025Article
- Wet-spun Ag/PEDOT: PSS composite fibers for high-sensitive SERS sensing and high electrical conducting.Scientific reports · 2024Article
- Microfluidics and Nanofluidics in Strong Light-Matter Coupling Systems.Nanomaterials (Basel, Switzerland) · 2024Review
- 2D material-based surface plasmon resonance biosensors for applications in different domains: an insight.Mikrochimica acta · 2024Review
- Unleashing the potential of tungsten disulfide: Current trends in biosensing and nanomedicine applications.Heliyon · 2024Review
- Topological Darkness in Optical Heterostructures: Prediction and Confirmation.ACS photonics · 2023Article
- Topological Darkness: How to Design a Metamaterial for Optical Biosensing with Ultrahigh Sensitivity.ACS nano · 2023Article
- A Genetic Algorithm for Universal Optimization of Ultrasensitive Surface Plasmon Resonance Sensors with 2D Materials.ACS omega · 2023Article
- MoSBiosensors · 2023Article
- Topological phase singularities in atomically thin high-refractive-index materials.Nature communications · 2022Article
- All-optical control of phase singularities using strong light-matter coupling.Nature communications · 2022Article
- 2D Material-Based Optical Biosensor: Status and Prospect.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Understanding breast cancer heterogeneity through non-genetic heterogeneity.Breast cancer (Tokyo, Japan) · 2021Review
- Nanophotonic biosensors harnessing van der Waals materials.Nature communications · 2021Review
- Nano-layered surface plasmon resonance-based highly sensitive biosensor for virus detection: A theoretical approach to detect SARS-CoV-2.AIP advances · 2021Article
- A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects.Nanomaterials (Basel, Switzerland) · 2021Review
- Graphene Plasmonics in Sensor Applications: A Review.Sensors (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
22 authors at 6 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasmonic biosensing has emerged as the most sensitive label-free technique to detect various molecular species in solutions and has already proved crucial in drug discovery, food safety and studies of bio-reactions. This technique relies on surface plasmon resonances in ~50 nm metallic films and the possibility to functionalize the surface of the metal in order to achieve selectivity. At the same time, most metals corrode in bio-solutions, which reduces the quality factor and darkness of plasmonic resonances and thus the sensitivity. Furthermore, functionalization itself might have a detrimental effect on the quality of the surface, also reducing sensitivity. Here we demonstrate that the use of graphene and other layered materials for passivation and functionalization broadens the range of metals which can be used for plasmonic biosensing and increases the sensitivity by 3-4 orders of magnitude, as it guarantees stability of a metal in liquid and preserves the plasmonic resonances under biofunctionalization. We use this approach to detect low molecular weight HT-2 toxins (crucial for food safety), achieving phase sensitivity~0.5 fg/mL, three orders of magnitude higher than previously reported. This proves that layered materials provide a new platform for surface plasmon resonance biosensing, paving the way for compact biosensors for point of care testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.