Evidence map›Paper›PMID 31888646›Full record

Observational studyHealth and quality of life outcomes2019

Health-related quality of life of patients diagnosed with COPD in Extremadura, Spain: results from an observational study.

María Merino, Renata Villoro, Álvaro Hidalgo-Vega, Concepción Carmona, Collaborative Working Group EPOC-Extremadura

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. The social determinants of health-related quality of life among people with chronic disease: a systematic literature review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  2. A Systematic Literature Review of the Humanistic Burden of COPD.International journal of chronic obstructive pulmonary disease
    Pooled it
  3. The Humanistic and Economic Burden of COPD Patients in Urban China: A Propensity Score Matching Study.International journal of chronic obstructive pulmonary disease · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

María MerinoFundación Weber, Calle Moreto 17, 5 D, 28014, Madrid, Spain. maria.merino@weber.org.es.ORCID http://orcid.org/0000-0002-5769-1821
Renata VilloroFundación Weber, Calle Moreto 17, 5 D, 28014, Madrid, Spain.
Álvaro Hidalgo-VegaFundación Weber, Calle Moreto 17, 5 D, 28014, Madrid, Spain.
Concepción CarmonaServicio Extremeño de Salud, Avenida de las Américas 2, 06800 Mérida, Badajoz, Spain.
Collaborative Working Group EPOC-Extremadura
Weber · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOPD is a high prevalence chronic disease that involves large reductions of health-related quality of life (HRQL) of patients. This study aims to describe the HRQL of patients with COPD in Extremadura (Spain).

methodsThis is a cross-sectional observational study carried out using a representative sample of patients diagnosed with COPD in Extremadura. The inclusion criteria were patients of legal age, diagnosed with COPD at least 12 months prior to the visit, residing in Extremadura, with electronic medical records available for the 12 months prior to the visit and providing informed consent. The intervention aimed to elicit HRQL indicators obtained from two validated questionnaires: EuroQol - 5 Dimensions - 5 Levels (EQ-5D-5L), and St. George's Respiratory Questionnaire-COPD (SGRQ-C). The main outcome measures were general HRQL (utility and visual analogue scale) and specific quality of life of COPD patients (total score and three component scores: Symptoms, Activity, and Impacts). Stepwise multiple regression analysis was applied to evaluate the association of EQ-5D-5L and SGRQ-C with respect to clinical and sociodemographic characteristics of the patients.

resultsWe recruited 386 patients (mean age 71.8 ± 10.3 years, 76.2% males). In the EQ-5D-5L, participants reported greater problems with respect to mobility (56.5%) and pain/discomfort (48.2%). The mean utility was 0.72 ± 0.31, and the SGRQ-C total score was 40.9 ± 25.0. The results of both questionnaires were associated with number of exacerbations in the last 12 months, level of COPD severity, gender, and education level of the patient (p < 0.05).

conclusionsThe results for both utility and total SGRQ-C score indicate that having suffered exacerbations in the last year, presenting a higher level of severity, being a woman, and having a low education level are related to worse HRQL in patients with COPD.

Indexed as

Quality of LifeAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSex FactorsSpainSurveys and QuestionnairesEQ-5D-5LHealth-related quality of lifeObstructive pulmonary diseasePrimary careSGRQ-CSpain

Identifiers

PMID31888646
PMCPMC6937847
OpenAlexW2997720458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.