Evidence map›Paper›PMID 31888580›Full record

ArticleBMC pulmonary medicine2019

Size-adjusted muscle power and muscle metabolism in patients with cystic fibrosis are equal to healthy controls - a case control study.

Katharina Ruf, Meinrad Beer, Herbert Köstler, Andreas Max Weng, Henning Neubauer, Alexander Klein, Kathleen Platek, Kristina Roth, Ralph Beneke, Helge Hebestreit

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katharina RufUniversity Children's Hospital Würzburg, University of Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Germany. ruf_k@ukw.de.ORCID http://orcid.org/0000-0001-8256-8123
Meinrad BeerDepartment of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany.
Herbert KöstlerDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.
Andreas Max WengDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.
Henning NeubauerDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.
Alexander KleinUniversity Children's Hospital Würzburg, University of Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
Kathleen PlatekUniversity Children's Hospital Würzburg, University of Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
Kristina RothUniversity Children's Hospital Würzburg, University of Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
Ralph BenekeInstitut für Sportwissenschaft und Motologie, Philipps Universität Marburg, Marburg, Germany.
Helge HebestreitUniversity Children's Hospital Würzburg, University of Würzburg, Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
University of Würzburg · DEPhilipps University of Marburg · DE

Funding

Deutsche Forschungsgemeinschaft N/AMukoviszidose e.V. n/a
6 · The paper itself

Abstract

backgroundSkeletal muscle function dysfunction has been reported in patients with cystic fibrosis (CF). Studies so far showed inconclusive data whether reduced exercise capacity is related to intrinsic muscle dysfunction in CF.

methodsTwenty patients with CF and 23 age-matched controls completed an incremental cardiopulmonary cycling test. Further, a Wingate anaerobic test to assess muscle power was performed. In addition, all participants completed an incremental knee-extension test with

resultsPatients with CF showed a reduced exercise capacity in the incremental cardiopulmonary cycling test (VO

conclusionsThe lower absolute muscle power in patients with CF compared to controls is exclusively explained by the reduced muscle size in this study. No evidence was found for an intrinsic skeletal muscle dysfunction due to primary alterations of muscle metabolism.

Indexed as

Muscle StrengthAdolescentAdultCase-Control StudiesChildCystic FibrosisFemaleHumansMaleMuscle, SkeletalOrgan SizeYoung AdultCystic fibrosisExercise capacityLung diseaseMRI spectroscopyMuscle functionMuscle powerPhosphorylation

Identifiers

PMID31888580
PMCPMC6937634
OpenAlexW2998301101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.