Evidence map›Paper›PMID 31888223›Full record

ReviewInternational journal of molecular sciences2019

Partners in Crime: Towards New Ways of Targeting Calcium Channels.

Lucile Noyer, Loic Lemonnier, Pascal Mariot, Dimitra Gkika

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Chaperone Sigma1R and Antidepressant Effect.International journal of molecular sciences · 2020
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lucile NoyerUniv. Lille, Inserm, U1003-PHYCEL-Physiologie Cellulaire, F-59000 Lille, France.
Loic LemonnierUniv. Lille, Inserm, U1003-PHYCEL-Physiologie Cellulaire, F-59000 Lille, France.
Pascal MariotUniv. Lille, Inserm, U1003-PHYCEL-Physiologie Cellulaire, F-59000 Lille, France.
Dimitra GkikaUniv. Lille, Inserm, U1003-PHYCEL-Physiologie Cellulaire, F-59000 Lille, France.ORCID 0000-0001-8612-0836
Inserm · FR

Funding

Association pour la Recherche sur les Tumeurs de la Prostate 2018Institut National de la Santé et de la Recherche Médicale 1003Institut Universitaire de France 2017
6 · The paper itself

Abstract

The characterization of calcium channel interactome in the last decades opened a new way of perceiving ion channel function and regulation. Partner proteins of ion channels can now be considered as major components of the calcium homeostatic mechanisms, while the reinforcement or disruption of their interaction with the channel units now represents an attractive target in research and therapeutics. In this review we will focus on the targeting of calcium channel partner proteins in order to act on the channel activity, and on its consequences for cell and organism physiology. Given the recent advances in the partner proteins' identification, characterization, as well as in the resolution of their interaction domain structures, we will develop the latest findings on the interacting proteins of the following channels: voltage-dependent calcium channels, transient receptor potential and ORAI channels, and inositol 1,4,5-trisphosphate receptor.

Indexed as

Molecular Targeted TherapyAnimalsCalciumCalcium Channel BlockersCalcium ChannelsHumansModels, BiologicalProtein BindingCalciumCalcium Channel BlockersCalcium ChannelsCaV channeldomain interactionsIP3RRapsigma receptorTCAFTRP channel

Identifiers

PMID31888223
PMCPMC6940757
OpenAlexW2995638756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.