Genome-Wide Analysis of Cyclophilin Proteins in 21 Oomycetes.

Yan Zhang, Kyle Fletcher, Rongkui Han, Richard Michelmore, Ruiwu Yang

Open access · goldAbstract read

In one paragraph

Article in Pathogens (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

Peptide Extracts from Seven Medicinal Plants Discovered to Inhibit OomycetePlants (Basel, Switzerland) · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yan ZhangCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.

Kyle FletcherGenome Center, University of California, Davis, CA 95616, USA.

Rongkui HanGenome Center, University of California, Davis, CA 95616, USA.

Richard MichelmoreGenome Center, University of California, Davis, CA 95616, USA.

Ruiwu YangCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0002-1346-6235

University of California, Davis · USSichuan Agricultural University · CN

Funding

The China Scholarship Council (CSC) N/A

6 · The paper itself

Abstract

Cyclophilins (CYPs), a highly-conserved family of proteins, belong to a subgroup of immunophilins. Ubiquitous in eukaryotes and prokaryotes, CYPs have peptidyl-prolyl cis-trans isomerase (PPIase) activity and have been implicated as virulence factors in plant pathogenesis by oomycetes. We identified 16 CYP orthogroups from 21 diverse oomycetes. Each species was found to encode 15 to 35 CYP genes. Three of these orthogroups contained proteins with signal peptides at the N-terminal end, suggesting a role in secretion. Multidomain analysis revealed five conserved motifs of the CYP domain of oomycetes shared with other eukaryotic PPIases. Expression analysis of CYP proteins in different asexual life stages of the hemibiotrophic

Indexed as

cyclophilineffectoroomycetePhytophthoraPlasmopara

Identifiers

PMID31888032

DOI10.3390/pathogens9010024

PMCPMC7168621

OpenAlexW2997248063

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.