Evidence map›Paper›PMID 31888018›Full record

ArticleAnimals : an open access journal from MDPI2019

Whole-Genome Signatures of Selection in Sport Horses Revealed Selection Footprints Related to Musculoskeletal System Development Processes.

Siavash Salek Ardestani, Mehdi Aminafshar, Mohammad Bagher Zandi Baghche Maryam, Mohammad Hossein Banabazi, Mehdi Sargolzaei, Younes Miar

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Siavash Salek ArdestaniDepartment of Animal Science, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
Mehdi AminafsharDepartment of Animal Science, Science and Research Branch, Islamic Azad University, Tehran 1477893855, Iran.
Mohammad Bagher Zandi Baghche MaryamDepartment of Animal Science, University of Zanjan, Zanjan 4537138791, Iran.ORCID 0000-0001-9568-8933
Mohammad Hossein BanabaziDepartment of Biotechnology, Animal Science Research Institute of Iran (ASRI), Agricultural Research, Education & Extension Organization (AREEO), Karaj 3146618361, Iran.ORCID 0000-0002-7873-8123
Mehdi SargolzaeiDepartment of Pathobiology, Veterinary College, University of Guelph, Guelph, ON NIG2W1, Canada.
Younes MiarDepartment of Animal Science and Aquaculture, Dalhousie University, Truro, NS B2N5E3, Canada.ORCID 0000-0001-9933-5414
Islamic Azad University, Science and Research Branch · IRAgricultural Research & Education Organization · IRDalhousie University · CAUniversity of Guelph · CAUniversity of Zanjan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective breeding has led to gradual changes at the genome level of horses. Deciphering selective pressure patterns is progressive to understand how breeding strategies have shaped the sport horse genome; although, little is known about the genomic regions under selective pressures in sport horse breeds. The major goal of this study was to shed light on genomic regions and biological pathways under selective pressures in sport horses. In this study, whole-genome sequences of 16 modern sport and 35 non-sport horses were used to investigate the genomic selective signals of sport performance, by employing fixation index, nucleotide diversity, and Tajima's D approaches. A total number of 49 shared genes were identified using these approaches. The functional enrichment analysis for candidate genes revealed novel significant biological processes related to musculoskeletal system development, such as limb development and morphogenesis, having been targeted by selection in sport breeds.

Indexed as

horsemusculoskeletalnon-sportsignature of selectionsport

Identifiers

PMID31888018
PMCPMC7023322
OpenAlexW2998591982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.