Evidence map›Paper›PMID 31887399›Full record

ArticleJournal of pain and symptom management2020

Advanced Cancer Patients' Changes in Accurate Prognostic Understanding and Their Psychological Well-Being.

Login S George, Paul K Maciejewski, Andrew S Epstein, Megan Shen, Holly G Prigerson

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  11. 'I Don't Like Uncertainty, I Like to Know': How and why uveal melanoma patients consent to life expectancy prognostication.Health expectations : an international journal of public participation in health care and health policy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Login S GeorgeMemorial Sloan Kettering Cancer Center, New York, New York, USA.
Paul K MaciejewskiWeill Cornell Medicine, New York, New York, USA.
Andrew S EpsteinMemorial Sloan Kettering Cancer Center, New York, New York, USA; Weill Cornell Medicine, New York, New York, USA.
Megan ShenWeill Cornell Medicine, New York, New York, USA.
Holly G PrigersonWeill Cornell Medicine, New York, New York, USA. Electronic address: hgp2001@med.cornell.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
Quality of Death: Ethnic and Psychosocial InfluencesR01CA106370 · NCI · YALE UNIVERSITY · PI PRIGERSON, HOLLY GWEN · 2004 to 2015
$4.1M
Latino vs. Non-Latino Disparities in Advance Care Planning & End-of-Life CareR01MD007652 · NIMHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2014 to 2018
$1.9M
Psychiatric Disorder in Dying Patients &Their SurvivorsR01MH063892 · NIMH · YALE UNIVERSITY · PI JACOBS, SELBY C · 2002 to 2005
$1.9M
Communicating the Gist of Prognosis: Giving Information Simply and Transparently ("GIST") in Advanced CancerR21NR018693 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI EPSTEIN, ANDREW, PRIGERSON, HOLLY GWEN · 2019 to 2020
$488k
Automated Detection of Suicide Attempt Risk among Bereaved IndividualsR21MH121886 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2020 to 2021
$454k
Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience (EMPOWER) in Caregivers of ICU Cancer PatientsR21CA218313 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LICHTENTHAL, WENDY G., PRIGERSON, HOLLY GWEN · 2017 to 2018
$422k
NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA106370NCI NIH HHS R21 CA218313NCI NIH HHS R35 CA197730NCI NIH HHS T32 CA009461NIA NIH HHS P30 AG022845NIMHD NIH HHS R01 MD007652NIMH NIH HHS R01 MH063892NIMH NIH HHS R21 MH121886NINR NIH HHS R21 NR018693
6 · The paper itself

Abstract

contextClinicians often worry that patients' recognition of the terminal nature of their illness may impair psychological well-being.

objectivesTo determine if such recognition was associated with decrements to psychological well-being that persisted over time.

methodsAbout 87 patients with advanced cancer, with an oncologist-expected life expectancy of less than six months, were assessed before and after an oncology visit to discuss cancer restaging scan results and again at follow-up (median time between assessments, approximately six weeks). Prognostic understanding (PU) was assessed at previsit and postvisit, and a change score was computed. Psychological well-being was assessed at pre, post, and follow-up, and two change scores were computed (post minus pre; follow-up minus post).

resultsChanges toward more accurate PU was associated with a corresponding initial decline in psychological well-being (r = -0.33; P < 0.01) but thereafter was associated with subsequent improvements (r = 0.40; P < 0.001). This pattern remained controlling for potential confounds. Patients showed different patterns of psychological well-being change (F = 3.07, P = 0.05; F = 6.54, P < 0.01): among patients with improved PU accuracy, well-being initially decreased but subsequently recovered; by contrast, among patients with stable PU accuracy, well-being remained relatively unchanged, and among patients with decrements in PU accuracy, well-being initially improved but subsequently declined.

conclusionImproved PU may be associated with initial decrements in psychological well-being, followed by patients rebounding to baseline levels. Concerns about lasting psychological harm may not need to be a deterrent to having prognostic discussions with patients.

Indexed as

NeoplasmsOncologistsHumansLife ExpectancyMedical OncologyPrognosisadaptationcomprehensionlife expectancylongitudinal studiesPrognosispsychological

Identifiers

PMID31887399
PMCPMC7186137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.