Evidence map›Paper›PMID 31887205›Full record

ArticlePloS one2019

A single institution experience of the treatment of pancreatic ductal carcinoma: The demand and the role of radiation therapy.

Katsumaro Kubo, Koichi Wadasaki, Daisuke Komichi, Tamito Sasaki, Hiroyasu Yamada, Yasuhiro Matsugu, Toshiyuki Itamoto, Mihoko Doi, Katsunori Shinozaki

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katsumaro KuboDepartment of Radiation Oncology, Hiroshima High-Precision Radiotherapy Cancer Center, Hiroshima-shi, Hiroshima, Japan.ORCID 0000-0001-5601-8961
Koichi WadasakiDepartment of Radiation Oncology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Daisuke KomichiDepartment of Gastroenterology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Tamito SasakiDepartment of Gastroenterology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Hiroyasu YamadaDepartment of Gastroenterology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Yasuhiro MatsuguDepartment of Surgery, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Toshiyuki ItamotoDepartment of Surgery, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Mihoko DoiDepartment of Clinical Oncology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.
Katsunori ShinozakiDepartment of Clinical Oncology, Hiroshima Prefectural Hospital, Hiroshima-shi, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to demonstrate a single institution experience of treatment of pancreatic ductal carcinoma and to identify the role of radiation therapy. We assessed all patients who were diagnosed with pancreatic ductal carcinoma from January 2011 to December 2017. A total of 342 patients were enrolled. Thirteen, 131, 36, and 162 patients had stage I, II, III, and IV disease, respectively (UICC TNM, 7th edition). Among the patients with stages I-III disease, 94 underwent surgery, and the median overall survival (OS) was 33 months. Of patients with stages I-III disease who were not suitable for surgery, 58 patients received chemotherapy, and the median OS was 12 months. Among them, 17 patients received chemoradiotherapy added on chemotherapy and their OS was significantly better than that of patients who received chemotherapy alone. Of patients with stage IV disease, 111 received chemotherapy, and the median OS was 6 months. This study evaluated the demand, role, and outcome of each treatment modality and demonstrated a single institution experience of treatment of pancreatic ductal carcinoma. The demand and role of radiation therapy remained small; however, radiation therapy might have some importance as a local treatment.

Indexed as

AgedAged, 80 and overCarcinoma, Pancreatic DuctalChemoradiotherapyChemotherapy, AdjuvantFemaleFollow-Up StudiesHealth Services Needs and DemandHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingPalliative CarePancreatectomyPancreatic Neoplasms

Identifiers

PMID31887205
PMCPMC6936878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.