Observational studyPloS one2019
The correlation between optical coherence tomography retinal shape irregularity and axial length.
Observational study in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Correlation of Patient-Reported Symptoms With Rhinogram Features Beyond Simple Airway Resistance.The Annals of otology, rhinology, and laryngology · 2026Article
- RPE Curvature Can Screen for Early and Intermediate AMD.Investigative ophthalmology & visual science · 2024Article
- Incidence and Risk Factors for Retinal Detachment Following Pediatric Cataract Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Swept-Source OCT Mid-Peripheral Retinal Irregularity in Retinal Detachment and Posterior Vitreous Detachment Eyes.Bioengineering (Basel, Switzerland) · 2023Article
- Retinal Shape-Based Classification of Retinal Detachment and Posterior Vitreous Detachment Eyes.Ophthalmology and therapy · 2023Article
- Myopia induces meridional growth asymmetry of the retina: a pilot study using wide-field swept-source OCT.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe the retinal contour in optical coherence tomography (OCT) images, and report the relationship between retinal contour and axial length.
methodsRetinal contour was defined by the path of the retinal pigment epithelial (RPE) line in macular and extra-macular OCTs of 70 eyes of 70 participants recruited from ophthalmology clinics in South Australia. The shape of this contour was described by the best-fit curvature (K), and Fourier analysis of the difference between K and the RPE. The Fourier transformation was summarised by total difference (sumdiff), maximum single frequency difference (MaxE), and root mean square difference (rmse) between each B scan residual and the average normal. All-of-eye and regional median and interquartile range (IQR) shape features were correlated to axial length.
resultsRetinal shape irregularity measured by Fourier transformation correlated with axial length: all-of-eye median and IQR sumdiff (ρ = 0.66 and ρ = 0.60 respectively), median and IQR rmse (ρ = 0.67 and ρ = 0.48), median MaxE (ρ = 0.61), and IQR K (ρ = 0.61) all correlated with axial length. Correlation with axial length was also seen in these parameters for 11 of 17 regions. Retinal irregularity was greatest at the macula and in inferior regions.
conclusionRetinal OCT shape becomes increasingly irregular as axial length increases. The range of curvature correlates with axial length, while median curvature does not.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.