Evidence map›Paper›PMID 31887182›Full record

SynthesisPloS one2019

Effects of experimentally induced fatigue on healthy older adults' gait: A systematic review.

Paulo Cezar Rocha Dos Santos, Fabio Augusto Barbieri, Inge Zijdewind, Lilian Teresa Bucken Gobbi, Claudine Lamoth, Tibor Hortobágyi

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The effect of exercise-induced muscle fatigue on gait parameters among older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Analyzing population-level trials as N-of-1 trials: An application to gait.Contemporary clinical trials communications · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Gait analysis under the lens of statistical physics.Computational and structural biotechnology journal · 2022
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Paulo Cezar Rocha Dos SantosCenter for Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-7378-1897
Fabio Augusto BarbieriHuman Movement Research Laboratory (MOVI-LAB), Graduate Program in Movement Sciences, Department of Physical Education, São Paulo State University (UNESP), Bauru, Brazil.
Inge ZijdewindDepartment of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Lilian Teresa Bucken GobbiPosture and Gait Studies Laboratory (LEPLO), Graduate Program in Movement Sciences, Institute of Biosciences, São Paulo State University (UNESP), Rio Claro, Brazil.ORCID 0000-0003-3984-3403
Claudine LamothCenter for Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Tibor HortobágyiCenter for Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhile fatigue is ubiquitous in old age and visibly interferes with mobility, studies have not yet examined the effects of self-reported fatigue on healthy older adults' gait. As a model that simulates this daily phenomenon, we systematically reviewed eleven studies that compared the effects of experimentally induced muscle and mental performance fatigability on gait kinematics, variability, kinetics, and muscle activity in healthy older adults.

methodsWe searched for studies in databases (PubMed and Web of Science) using Fatigue, Gait, and Clinical conditions as the main terms and extracted the data only from studies that experimentally induced fatigue by sustained muscle or mental activities in healthy older adults.

resultsEleven studies were included. After muscle performance fatigability, six of nine studies observed increases in stride length, width, gait velocity (Effect Size [ES] range: 0.30 to 1.22), inter-stride trunk acceleration variability (ES: 2.06), and ankle muscle coactivation during gait (ES: 0.59, n = 1 study). After sustained mental activity, the coefficient of variation of stride outcomes increased (ES: 0.59 to 0.67, n = 1 study) during dual-task but not single-task walking.

conclusionMuscle performance fatigability affects spatial and temporal features of gait and, mainly, inter-stride trunk acceleration variability. In contrast, sustained mental activity tends only to affect step variability during dual tasking. A critical and immediate step for future studies is to determine the effects of self-reported fatigue on gait biomechanics and variability in healthy older adults to verify the viability of experimentally induced fatigue as a model for the study of gait adaptability in old age.

Indexed as

Adaptation, PhysiologicalAgedAgingBiomechanical PhenomenaFatigueFemaleGaitHumansMaleMental FatigueMuscle FatigueWalking

Identifiers

PMID31887182
PMCPMC6936857
OpenAlexW2997236039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.