ArticlePloS one2019
Comparative de novo transcriptomics and untargeted metabolomic analyses elucidate complicated mechanisms regulating celery (Apium graveolens L.) responses to selenium stimuli.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Transcriptional profiling of glutathione metabolism and the glutathione redox cycle ofFrontiers in plant science · 2026Article
- An attapulgite-Bacillus amyloliquefaciens biocontrol agent increases growth and medicinal metabolite content in Angelica sinensis by modulating hormonal and phenylpropanoid pathways.BMC plant biology · 2025Article
- Comprehensive review of multiomics applications and remediation of plant heavy metal toxicity.Stress biology · 2025Review
- Physiological and Transcriptome Analysis Provide Insights into the Effects of Low and High Selenium on Methionine and Starch Metabolism in Rice Seedlings.International journal of molecular sciences · 2025Article
- Underground Reservoirs Regulate the Composition and Metabolism of Microbial Community in Coal Mine Water.ACS omega · 2024Article
- Leveraging multi-omics tools to comprehend responses and tolerance mechanisms of heavy metals in crop plants.Functional & integrative genomics · 2024Review
- Novel Tri-Segmented Rhabdoviruses: A Data Mining Expedition Unveils the Cryptic Diversity of Cytorhabdoviruses.Viruses · 2023Article
- A comprehensive review on genomic resources in medicinally and industrially important major spices for future breeding programs: Status, utility and challenges.Current research in food science · 2023Review
- Integrative Transcriptome and Proteome Analysis Reveals the Absorption and Metabolism of Selenium in Tea Plants [Frontiers in plant science · 2022Article
- Comparative physiological analyses and the genetic basis reveal heat stress responses mechanism among differentFrontiers in plant science · 2022Article
- Origin, evolution, breeding, and omics of Apiaceae: a family of vegetables and medicinal plants.Horticulture research · 2022Article
- Impact of Genomic and Transcriptomic Resources on Apiaceae Crop Breeding Strategies.International journal of molecular sciences · 2021Review
- Comparative physiological and full-length transcriptome analyses reveal the molecular mechanism of melatonin-mediated salt tolerance in okra (Abelmoschus esculentus L.).BMC plant biology · 2021Article
- Comparative transcriptomic analyses of normal and peloric mutant flowers in Cymbidium goeringii Rchb.f identifies differentially expressed genes associated with floral development.Molecular biology reports · 2021Article
- Advances in "Omics" Approaches for Improving Toxic Metals/Metalloids Tolerance in Plants.Frontiers in plant science · 2021Review
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Presently, concern regarding the effects of selenium (Se) on the environment and organisms worldwide is increasing. Too much Se in the soil is harmful to plants. In this study, Illumina RNA sequencing and the untargeted metabolome of control and Se-treated celery seedlings were analyzed. In total, 297,911,046 clean reads were obtained and assembled into 150,218 transcripts (50,876 unigenes). A total of 36,287 unigenes were annotated using different databases. Additionally, 8,907 differentially expressed genes, including 5,319 up- and 3,588 downregulated genes, were identified between mock and Se-treated plants. "Phenylpropanoid biosynthesis" was the most enriched KEGG pathway. A total of 24 sulfur and selenocompound metabolic unigenes were differentially expressed. Furthermore, 1,774 metabolites and 237 significant differentially accumulated metabolites were identified using the untargeted metabolomic approach. We conducted correlation analyses of enriched KEGG pathways of differentially expressed genes and accumulated metabolites. Our findings suggested that candidate genes and metabolites involved in important biological pathways may regulate Se tolerance in celery. The results increase our understanding of the molecular mechanism responsible for celery's adaptation to Se stress.
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