Evidence map›Paper›PMID 31887029›Full record

ArticleJournal of the American Chemical Society2020

Corona Exchange Dynamics on Carbon Nanotubes by Multiplexed Fluorescence Monitoring.

Rebecca L Pinals, Darwin Yang, Alison Lui, Wendy Cao, Markita P Landry

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 76 citations in OpenAlex.

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  14. Concerning the photophysics of fluorophores towards tailored bioimaging compounds: a case study involving S100A9 inflammation markers.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rebecca L PinalsDepartment of Chemical and Biomolecular Engineering , University of California at Berkeley , Berkeley , California 94720 , United States.
Darwin YangDepartment of Chemical and Biomolecular Engineering , University of California at Berkeley , Berkeley , California 94720 , United States.
Alison LuiDepartment of Chemical and Biomolecular Engineering , University of California at Berkeley , Berkeley , California 94720 , United States.
Wendy CaoDepartment of Chemistry , University of California at Berkeley , Berkeley , California 94720 , United States.
Markita P LandryDepartment of Chemical and Biomolecular Engineering , University of California at Berkeley , Berkeley , California 94720 , United States.ORCID 0000-0002-5832-8522
University of California, Berkeley · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
Novel optical probe for dopamine release in neural circuitsR21EY029405 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI FELLER, MARLA, LANDRY, MARKITA · 2018 to 2019
$428k
Optical montoring of modulatory neurotransmitter levels using new infrared nanonsensorsR21DA044010 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILBRECHT, LINDA E · 2017 to 2018
$323k
Imaging presynaptic correlates of cocaine locomotor sensitization with near infrared catecholamine nanosensorsR03DA052810 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2021 to 2021
$223k
NEI NIH HHS R21 EY029405NIDA NIH HHS R03 DA052810NIDA NIH HHS R21 DA044010NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Noncovalent adsorption of DNA on nanoparticles has led to their widespread implementation as gene delivery tools and optical probes. Yet, the behavior and stability of DNA-nanoparticle complexes once applied in biomolecule-rich, in vivo environments remains unpredictable, whereby biocompatibility testing usually occurs in serum. Here, we demonstrate time-resolved measurements of exchange dynamics between solution-phase and adsorbed corona-phase DNA and protein biomolecules on single-walled carbon nanotubes (SWCNTs). We capture real-time binding of fluorophore-labeled biomolecules, utilizing the SWCNT surface as a fluorescence quencher, and apply this corona exchange assay to study protein corona dynamics on ssDNA-SWCNT-based dopamine sensors. We study exchange of two blood proteins, albumin and fibrinogen, adsorbing to and competitively displacing (GT)

Indexed as

KineticsLigandsNanotubes, CarbonProtein CoronaSpectrometry, FluorescenceLigandsNanotubes, CarbonProtein Corona

Identifiers

PMID31887029
PMCPMC10493162
OpenAlexW2997407559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.