Evidence map›Paper›PMID 31886907›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2020

Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture.

Jarred Kaiser, Brett Allaire, Paul M Fein, Darlene Lu, Alexander Adams, Douglas P Kiel, Mohamed Jarraya, Ali Guermazi, Serkalem Demissie, Elizabeth J Samelson and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  8. Frontiers in bioengineering and biotechnology · 2024
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  14. The micro-structural analysis of lumbar vertebrae in alcoholic liver cirrhosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jarred KaiserDepartment of Mechanical Engineering, Boston University, Boston, MA, USA.ORCID 0000-0001-9373-2961
Brett AllaireDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Paul M FeinDepartment of Mechanical Engineering, Boston University, Boston, MA, USA.
Darlene LuDepartment of Biostatistics, Boston University, Boston, MA, USA.
Alexander AdamsDepartment of Mechanical Engineering, Boston University, Boston, MA, USA.
Douglas P KielDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Mohamed JarrayaDepartment of Radiology, Boston University School of Medicine, Boston, MA, USA.
Ali GuermaziDepartment of Radiology, Boston University School of Medicine, Boston, MA, USA.
Serkalem DemissieDepartment of Biostatistics, Boston University, Boston, MA, USA.
Elizabeth J SamelsonDepartment of Biostatistics, Boston University, Boston, MA, USA.ORCID 0000-0003-1086-1560
Mary L BouxseinDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Elise F MorganDepartment of Mechanical Engineering, Boston University, Boston, MA, USA.
Boston University · USBeth Israel Deaconess Medical Center · US

Funding

3-D Visualization and Prediction of Vertebral FracturesR01AR054620 · NIAMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MORGAN, ELISE F · 2008 to 2025
$6.7M
Biomechanics of Vertebral Fracture: The Framingham QCT StudyR01AR053986 · NIAMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUXSEIN, MARY L · 2007 to 2016
$5.4M
Mechansims and Clinical Importance of Hyperkyphosis:The Framingham StudyR01AG041658 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2011 to 2015
$2.6M
Volumetric Bone Density and Vascular Calcification: The Framingham QCT StudyK01AR053118 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2007 to 2011
$481k
NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INIAMS NIH HHS K01 AR053118NIAMS NIH HHS R01 AR053986NIAMS NIH HHS R01 AR054620NIA NIH HHS R01 AG041658
6 · The paper itself

Abstract

The spatial heterogeneity in trabecular bone density within the vertebral centrum is associated with vertebral strength and could explain why volumetric bone mineral density (vBMD) exhibits low sensitivity in identifying fracture risk. This study evaluated whether the heterogeneity and spatial distribution of trabecular vBMD are associated with prevalent vertebral fracture. We examined the volumetric quantitative computed tomography (QCT) scans of the L

Indexed as

Spinal FracturesBone DensityHumansLumbar VertebraeTomography, X-Ray ComputedBIOMECHANICSBONE QCT/μCTFRACTURE RISK ASSESSMENTGENERAL POPULATION STUDIESOSTEOPOROSIS

Identifiers

PMID31886907
PMCPMC7145746
OpenAlexW2997640083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.