ArticleThe journal of nutrition, health & aging2020
Anticholinergic Load and Nutritional Status in Older Individuals.
Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Polypharmacy and Malnutrition Management of Elderly Perioperative Patients with Cancer: A Systematic Review.Nutrients · 2021Pooled it
- Nonsteroidal anti-inflammatory drug use is associated with improved activities of daily living and rehabilitation in older adult patients following a fracture: a retrospective cohort study.Journal of pharmaceutical health care and sciences · 2025Article
- Anticholinergic drug exposure is associated with prevalence, worsening and incidence of dysphagia among hospitalized older adults.The journal of nutrition, health & aging · 2025Article
- Exploring the impact of anticholinergic burden on urinary independence: insights from a post-stroke cohort of older adults.International journal of clinical pharmacy · 2024Observational
- Anticholinergic Load Is Associated with Swallowing Dysfunction in Convalescent Older Patients after a Stroke.Nutrients · 2022Article
- Deprescribing Leads to Improved Energy Intake among Hospitalized Older Sarcopenic Adults with Polypharmacy after Stroke.Nutrients · 2022Article
- Association of polypharmacy at hospital discharge with nutritional intake, muscle strength, and activities of daily living among older patients undergoing convalescent rehabilitation after stroke.Japanese journal of comprehensive rehabilitation science · 2022Article
- Does age alone negatively predict the outcome of sacral neuromodulation? A single-centre retrospective observational study.BMC urology · 2020Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe association between anticholinergic load-based Anticholinergic Risk Scale scores and nutritional status is unclear in Japanese patients. The aim of this study was to establish whether anticholinergic load affects the nutritional status of geriatric patients in convalescent stages.
designRetrospective longitudinal cohort study.
settingConvalescent rehabilitation wards.
participantsOf the 1490 patients aged ≥65 years who were discharged from convalescent rehabilitation wards between July 2010 and October 2018, 908 patients met the eligibility criteria. They were categorized according to the presence or absence of increased anticholinergic load from admission to discharge. MEASUREMENTS: Demographic data, laboratory data, the Functional Independence Measure were analyzed between the groups. The primary outcome was Geriatric Nutritional Risk Index (GNRI) at discharge. Multiple linear regression analysis was performed to analyze the relationship between anticholinergic load and GNRI at discharge.
resultsMultiple linear regression analysis after adjusting for confounding factors revealed that anticholinergic load was independently and negatively correlated with GNRI at discharge. Particularly, the use of chlorpromazine, hydroxyzine, haloperidol, metoclopramide, risperidone, etc. increased significantly from admission to discharge.
conclusionIncreased anticholinergic load during hospitalization may be a predictor of nutritional status in geriatric patients.
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