Evidence map›Paper›PMID 31886770›Full record

ArticleeLife2019

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.

Avinash B Patel, Camille M Moore, Basil J Greber, Jie Luo, Stefan A Zukin, Jeff Ranish, Eva Nogales

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome.Acta crystallographica. Section D, Structural biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Avinash B Patel *Biophysics Graduate Group, University of California, Berkeley, Berkeley, United States.ORCID 0000-0001-9140-8375
Camille M Moore *Molecular and Cell Biology Department, University of California, Berkeley, Berkeley, United States.
Basil J Greber *Molecular Biophysics and Integrative Bio-Imaging Division, Lawrence Berkeley National Laboratory, Berkeley, United States.ORCID 0000-0001-9379-7159
Jie LuoThe Institute for Systems Biology, Seattle, United States.
Stefan A ZukinChemistry Department, University of California, Berkeley, Berkeley, United States.
Jeff RanishThe Institute for Systems Biology, Seattle, United States.
Eva NogalesMolecular Biophysics and Integrative Bio-Imaging Division, Lawrence Berkeley National Laboratory, Berkeley, United States.ORCID 0000-0001-9816-3681
Institute for Systems Biology · USQB3 · USUniversity of California, Berkeley · USLawrence Berkeley National Laboratory · US

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Structural studies of function and regulation of microtubules and transcriptional gene expression machineryR35GM127018 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Eva Nogales · 2018 to 2026
$4.3M
Structural Studies of the Eukaryotic Transcription Initiation MachineryR01GM063072 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI NOGALES, EVA · 2001 to 2016
$2.5M
TFIIH and Transcription RegulationR01GM110064 · NIGMS · UNIVERSITY OF COLORADO · PI RANISH, JEFFREY A, TAATJES, DYLAN J · 2016 to 2019
$2.2M
An LXR protein interaction network controlling macrophage lipid transporter expression in response to inflammatory-lipid crosstalkR01HL133678 · NHLBI · INSTITUTE FOR SYSTEMS BIOLOGY · PI RANISH, JEFFREY A · 2016 to 2019
$1.8M
NHLBI NIH HHS R01 HL133678NIGMS NIH HHS R01 GM063072NIGMS NIH HHS R01 GM110064NIGMS NIH HHS R01-GM110064NIGMS NIH HHS R01- GM110064NIGMS NIH HHS R01-GM63072NIGMS NIH HHS R01-HL133678NIGMS NIH HHS R35 GM127018NIGMS NIH HHS R35-GM127018NIGMS NIH HHS U24 GM129547NIH HHS U24GM129547
6 · The paper itself

Abstract

Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The

Indexed as

Cell Cycle ProteinsChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneCryoelectron MicroscopyDNA-Binding ProteinsDNA, FungalDNA RepairMultiprotein ComplexesNucleosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsCell Cycle ProteinsChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDNA, FungalMultiprotein ComplexesNPL6 protein, S cerevisiaeNucleosomesRSC complex, S cerevisiaeSaccharomyces cerevisiae ProteinsSfh1 protein, S cerevisiaeSWI-SNF-B chromatin-remodeling complexTranscription Factorschromatinchromatin remodelingcryo-EMmolecular biophysicsS. cerevisiaestructural biologytranscription

Identifiers

PMID31886770
PMCPMC6959994
OpenAlexW2997966709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.