ArticleeLife2019
Estimating effectiveness of case-area targeted response interventions against cholera in Haiti.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis.PLoS medicine · 2023Pooled it
- A Review of the Ring Trial Design for Evaluating Ring Interventions for Infectious Diseases.Epidemiologic reviews · 2022Pooled it
- Case-area targeted preventive interventions to interrupt cholera transmission: Current implementation practices and lessons learned.PLoS neglected tropical diseases · 2021Pooled it
- Randomized Controlled Trial of the Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Cholera Rapid Response Program to Reduce Diarrheal Diseases in Bangladesh.International journal of environmental research and public health · 2022Trial
- Epidemicity conditions in spatial models of infectious diseases.Bollettino della Unione matematica italiana (2008) · 2026Article
- Water Insecurity, Sociopolitical Instability, and Resurgence of Cholera in Haiti, 2022: An Outbreak Investigation.The American journal of tropical medicine and hygiene · 2025Article
- Optimizing the implementation of case-area targeted interventions during cholera outbreaks with context-specific delivery mechanisms.PLoS neglected tropical diseases · 2025Review
- Case-area targeted interventions and free chlorine residual in household drinking water: An observational cohort study during a cholera outbreak in Northeast Nigeria.PLoS neglected tropical diseases · 2025Observational
- Outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- Case-area targeted interventions during a large-scale cholera epidemic: A prospective cohort study in Northeast Nigeria.PLoS medicine · 2024Observational
- Informing policy via dynamic models: Cholera in Haiti.PLoS computational biology · 2024Article
- Reviving health mediation during the COVID-19 crisis and beyond: an implementation study in deprived neighbourhoods of Marseille, France.Frontiers in public health · 2024Article
- A Quantitative and Qualitative Program Evaluation of a Case-Area Targeted Intervention to Reduce Cholera in Eastern Democratic Republic of the Congo.International journal of environmental research and public health · 2023Article
- Implementation of targeted cholera response activities, Cameroon.Bulletin of the World Health Organization · 2023Article
- Review
- Vibrio Infections and the Twenty-First Century.Advances in experimental medicine and biology · 2023Article
- Formative Research for the Development of the CHoBI7 Cholera Rapid Response Program for Cholera Hotspots in Bangladesh.International journal of environmental research and public health · 2022Article
- Article
- Epidemicity of cholera spread and the fate of infection control measures.Journal of the Royal Society, Interface · 2022Article
- Inference is bliss: Simulation for power estimation for an observational study of a cholera outbreak intervention.PLoS neglected tropical diseases · 2022Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case-area targeted interventions (CATIs) against cholera are conducted by rapid response teams, and may include various activities like water, sanitation, hygiene measures. However, their real-world effectiveness has never been established. We conducted a retrospective observational study in 2015-2017 in the Centre department of Haiti. Using cholera cases, stool cultures and CATI records, we identified 238 outbreaks that were responded to. After adjusting for potential confounders, we found that a prompt response could reduce the number of accumulated cases by 76% (95% confidence interval, 59 to 86) and the outbreak duration by 61% (41 to 75) when compared to a delayed response. An intense response could reduce the number of accumulated cases by 59% (11 to 81) and the outbreak duration by 73% (49 to 86) when compared to a weaker response. These results suggest that prompt and repeated CATIs were significantly effective at mitigating and shortening cholera outbreaks in Haiti.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.