Evidence map›Paper›PMID 31886728›Full record

ArticleCurrent eye research2020

Characterization of an Electronic Corneal Prosthesis System.

Sarah Y Shim, Songbin Gong, Victoria H Fan, Mark I Rosenblatt, Ahmed F Al-Qahtani, Michael G Sun, Qiang Zhou, Levi Kanu, Ibraim V Vieira, Charles Q Yu

Open access · greenAbstract read
In one paragraph

Article in Current eye research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Temperature Elevation in the Human Eye Due To Intraocular Projection Prosthesis Device.Journal of thermal science and engineering applications · 2021
    Article
  4. THERMAL ANALYSIS OF INTRAOCULAR ELECTRONIC DISPLAY PROJECTOR VISUAL PROSTHESIS.Numerical heat transfer. Part A, Applications · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sarah Y ShimElectrical and Computer Engineering, The University of Illinois Urbana Champaign , Champaign, IL, USA.
Songbin GongElectrical and Computer Engineering, The University of Illinois Urbana Champaign , Champaign, IL, USA.
Victoria H FanDepartment of Ophthalmology, Byers Eye Institute, Stanford University , Palo Alto, CA, USA.
Mark I RosenblattDepartment of Ophthalmology and Visual Sciences, The University of Illinois Chicago , Chicago, IL, USA.ORCID 0000-0001-8978-1955
Ahmed F Al-QahtaniDepartment of Ophthalmology and Visual Sciences, The University of Illinois Chicago , Chicago, IL, USA.
Michael G SunDepartment of Ophthalmology and Visual Sciences, The University of Illinois Chicago , Chicago, IL, USA.
Qiang ZhouDepartment of Ophthalmology and Visual Sciences, The University of Illinois Chicago , Chicago, IL, USA.
Levi KanuDepartment of Ophthalmology and Visual Sciences, The University of Illinois Chicago , Chicago, IL, USA.
Ibraim V VieiraDepartment of Ophthalmology, Byers Eye Institute, Stanford University , Palo Alto, CA, USA.
Charles Q YuDepartment of Ophthalmology, Byers Eye Institute, Stanford University , Palo Alto, CA, USA.
University of Illinois Chicago · USSmith-Kettlewell Eye Research Institute · USUniversity of Illinois Urbana-Champaign · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Minimally Invasive KeratoprosthesisK08EY027459 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YU, CHARLES · 2017 to 2020
$857k
NEI NIH HHS K08 EY027459NEI NIH HHS P30 EY001792
6 · The paper itself

Abstract

purposeCorneal opacity is a leading cause of reversible blindness worldwide. An electronic corneal prosthesis, or intraocular projector, could potentially restore high-quality vision without need for corneal clarity. MATERIALS AND

methodsFour intraocular projection systems were constructed from commercially available electronic components and encased in biocompatible plastic housing. They were tested for optical properties, biocompatibility, heat dissipation, waterproofing, and accelerated wear. A surgical implantation technique was developed.

resultsIntraocular projectors were produced of a size that can fit within the eye. Their optics produce better than 20/200 equivalent visual acuity. MTT assay demonstrated no cytotoxicity of devices

conclusionThis is the first study to demonstrate and characterize fully functional intraocular projection systems. This technology has the potential to be an important new tool in the treatment of intractable corneal blindness.

Indexed as

Prosthesis ImplantationVisual ProsthesisWearable Electronic DevicesBiocompatible MaterialsCorneaCorneal OpacityElectrical Equipment and SuppliesElectrodes, ImplantedHumansMaterials TestingProsthesis DesignVisual PerceptionBiocompatible MaterialsAlpha IMSArgusCorneal blindnesscornea transplantationkeratoprosthesismicrodisplayprojectorretinal prosthesis

Identifiers

PMID31886728
PMCPMC9997130
OpenAlexW2997465216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.