SynthesisAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2020
Genome-wide association study of shared liability to anxiety disorders in Army STARRS.
Synthesis in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03170362 (PRIME Care), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PRIME Care (PRecision Medicine In MEntal Health Care)
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.Nature genetics · 2026Pooled it
- Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings.Psychiatry and clinical neurosciences · 2022Pooled it
- Article
- Psychiatric genetics in the diverse landscape of Latin American populations.Nature genetics · 2025Review
- Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders.Psychiatry and clinical neurosciences · 2024Article
- Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.Nature genetics · 2024Article
- Using Alternative Definitions of Controls to Increase Statistical Power in GWAS.Behavior genetics · 2024Article
- Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders.medRxiv : the preprint server for health sciences · 2024Article
- Exploring the genetic and socioeconomic interplay between ADHD and anxiety disorders using Mendelian randomization.Frontiers in psychiatry · 2024Article
- Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies.Molecular psychiatry · 2023Review
- Pharmacogenetics of Dolutegravir Plasma Exposure Among Southern Africans With Human Immunodeficiency Virus.The Journal of infectious diseases · 2022Article
- Massively parallel techniques for cataloguing the regulome of the human brain.Nature neuroscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Anxiety disorders (ANX), namely generalized anxiety, panic disorder, and phobias, are common, etiologically complex syndromes that show increasing prevalence and comorbidity throughout adolescence and beyond. Few genome-wide association studies (GWAS) examining ANX risk have been published and almost exclusively in individuals of European ancestry. In this study, we phenotyped participants from the Army Study To Assess Risk and Resilience in Servicemembers (STARRS) to approximate DSM-based ANX diagnoses. We factor-analyzed those to create a single dimensional anxiety score for each subject. GWAS were conducted using that score within each of three ancestral groups (EUR, AFR, LAT) and then meta-analyzed across ancestries (N
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.