Evidence map›Paper›PMID 31886560›Full record

ArticleThe EMBO journal2020

Towards the unified principles of transcription termination.

Vladimir Svetlov, Evgeny Nudler

Abstract readNewsComment
In one paragraph

Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vladimir SvetlovDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.
Evgeny NudlerDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.ORCID 0000-0002-8811-3071

Funding

Transcription termination and gene regulation by Rho: Integrative analysisR01GM126891 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NUDLER, EVGENY A · 2018 to 2021
$2.3M
NIGMS NIH HHS R01 GM126891
6 · The paper itself

Abstract

Discovery of the role of bacterial RNase J1 in termination of transcription suggests common allosteric principles and mechanistic congruency of termination between bacteria and eukaryotes, in which an unrelated RNase Xrn2/Rat1 plays a similar role.

Indexed as

ExoribonucleasesTranscription Termination, GeneticAnimalsBacillus subtilisTorpedoTranscription, GeneticExoribonucleases

Identifiers

PMID31886560
PMCPMC6996497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.