Evidence map›Paper›PMID 31886155›Full record

ArticleCanadian journal of gastroenterology & hepatology2019

In Vivo Evaluation of Histopathological Alterations and Trace Metals Estimation of the Small Intestine in Bisphenol A-Intoxicated Rats.

Saira Ambreen, Tasleem Akhtar, Naila Hameed, Isbah Ashfaq, Nadeem Sheikh

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saira AmbreenCell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Lahore, Pakistan.
Tasleem AkhtarDepartment of Pharmacology, University of Health Sciences, Lahore, Pakistan.ORCID 0000-0002-4984-4373
Naila HameedCell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Lahore, Pakistan.
Isbah AshfaqCell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Lahore, Pakistan.
Nadeem SheikhCell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Lahore, Pakistan.ORCID 0000-0001-9503-9538
University of the Punjab · PKUniversity of Health Sciences Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BPA, a ubiquitously used plasticizer, has become one of the contaminants of emerging concern and causes many serious health implications in humans due to multiple exposure pathways. The current study was aimed at investigating the deformities of structures that arise by exposure of the small intestine to BPA through trace elements estimation of tissues as well as the study of serum profile. Two major groups of Wistar rats were established: one control group and the other experimental group, which was further divided into four groups based on dose (10 mg/kg/bodyweight and 25 mg/kg/bodyweight, respectively) and duration of exposure (6 and 12 weeks, respectively). Histological study of the small intestine showed the distorted structures in the experimental groups. The special staining performed illustrated the accumulation of calcium deposits in the small intestinal tissue in treated groups. Trace metals estimation showed a significant increase in the metallic content of sodium and iron and a decrease in the calcium content in the experimental groups (

Indexed as

AnimalsBenzhydryl CompoundsBisphenol A CompoundsIntestine, SmallMaleMetals, HeavyPhenolsRatsRats, WistarBenzhydryl Compoundsbisphenol ABisphenol A CompoundsMetals, HeavyPhenols

Identifiers

PMID31886155
PMCPMC6925935
OpenAlexW2996344716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.