Evidence map›Paper›PMID 31885916›Full record

ArticleCritical care research and practice2019

Beta-Blocker Therapy Preserves Normal Splenic T-Lymphocyte Numbers Reduced in Proportion to Sepsis Severity in a Sepsis Model.

Takeshi Suzuki, Kei Inoue, Toru Igarashi, Jungo Kato, Hiromasa Nagata, Takashige Yamada, Shizuka Minamishima, Hiroshi Morisaki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Lymphopenia in sepsis: a narrative review.Critical care (London, England) · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Takeshi SuzukiTokai University School of Medicine, Department of Anesthesiology, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.ORCID https://orcid.org/0000-0003-3703-9323
Kei InoueKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Toru IgarashiKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Jungo KatoKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Hiromasa NagataKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Takashige YamadaKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Shizuka MinamishimaKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Hiroshi MorisakiKeio University School of Medicine, Department of Anesthesiology, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Keio University Hospital · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphocyte cell death contributes to sepsis-induced immunosuppression, leading to poor prognosis. This study examined whether sepsis severity and beta-blocker therapy could affect the degree of T-lymphocyte cell death in a mouse model of sepsis. In the first control study, 20 animals were allocated to 4 groups: control group with sham operation (group C,

Identifiers

PMID31885916
PMCPMC6927051
OpenAlexW2995107663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.