Evidence map›Paper›PMID 31885874›Full record

ArticleCell discovery2019

Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro.

Clayton B Woodcock, Dan Yu, Taraneh Hajian, Jia Li, Yun Huang, Nan Dai, Ivan R Corrêa, Tao Wu, Masoud Vedadi, Xing Zhang and 1 more

Abstract read
In one paragraph

Article in Cell discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. FTO separation-of-function mutations alter mbioRxiv : the preprint server for biology · 2026
    Article
  2. Rewriting the RNA code: an mFrontiers in immunology · 2026
    Review
  3. Inhibition ofACS omega · 2025
    Article
  4. Article
  5. Article
  6. Inhibition ofbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Structures and mechanisms of the RNA mActa biochimica et biophysica Sinica · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Ghost authors revealed: The structure and function of human NWiley interdisciplinary reviews. RNA · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clayton B Woodcock1Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.
Dan Yu1Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.
Taraneh Hajian2Structural Genomics Consortium, University of Toronto, Toronto, ON Canada.
Jia Li3Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University, Houston, TX 77030 USA.
Yun Huang3Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University, Houston, TX 77030 USA.
Nan Dai4New England Biolabs, Inc, Ipswich, MA 01938 USA.
Ivan R Corrêa4New England Biolabs, Inc, Ipswich, MA 01938 USA.ORCID 0000-0002-3169-6878
Tao Wu5Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030 USA.ORCID 0000-0002-9859-4534
Masoud Vedadi2Structural Genomics Consortium, University of Toronto, Toronto, ON Canada.
Xing Zhang *1Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.
Xiaodong Cheng *1Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.

Funding

THREE-DIMENSIONAL STRUCTURE OF HHAI METHYLASER01GM049245 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHENG, XIAODONG · 1993 to 2017
$6.6M
TET-mediated epigenetic regulation in cardiac development.R01HL134780 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HUANG, YUN · 2018 to 2022
$1.9M
Role of TET dioxygenase associated immune mechanisms in cardiac injury and repairR01HL146852 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HUANG, YUN · 2019 to 2022
$1.7M
NHLBI NIH HHS R01 HL134780NHLBI NIH HHS R01 HL146852NIGMS NIH HHS R01 GM049245
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MethylationNucleosomes

Identifiers

PMID31885874
PMCPMC6928010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.