ArticleLight, science & applications2019
Full noncontact laser ultrasound: first human data.
Article in Light, science & applications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 88 citations in OpenAlex.
- Effective point spread function modeling of photoacoustic remote sensing microscopy towards resolution enhancement.Photoacoustics · 2026Article
- Neural networks for faster laser ultrasound tomography in tissue phantoms.Photoacoustics · 2026Article
- Holographic diffusers for endoluminal-scale optical ultrasound imaging.Journal of biomedical optics · 2026Article
- Laser Ultrasound Super-Resolution Imaging for Multi-Parametric Non-Invasive Volumetric Characterization of Brain Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- All-opticalPhotoacoustics · 2025Article
- Multi-photon, label-free photoacoustic and optical imaging of NADH in brain cells.Light, science & applications · 2025Article
- Spatial-offset pump-probe imaging of nonradiative dynamics at optical resolution.Science advances · 2025Article
- Hybrid transformer-CNN network-driven optical-scanning undersampling for photoacoustic remote sensing microscopy.Photoacoustics · 2025Article
- Non-contact electroacoustic tomography with optical interferometer for electroporation therapy monitoring.Applied physics letters · 2025Article
- Non-iterative model-based inversion for low channel-count optical ultrasound imaginga).The Journal of the Acoustical Society of America · 2024Article
- Non-contact photoacoustic imaging with a silicon photonics-based Laser Doppler Vibrometer.Scientific reports · 2024Article
- Towards clinical application of freehand optical ultrasound imaging.Scientific reports · 2024Article
- Development of a piezo stack - laser Doppler vibrometer sensing approach for characterizing shear wave dispersion and local viscoelastic property distributions.Mechanical systems and signal processing · 2024Article
- Online evolution of a phased array for ultrasonic imaging by a novel adaptive data acquisition method.Scientific reports · 2024Article
- Adapting the Time-Domain Synthetic Aperture Focusing Technique (T-SAFT) to Laser Ultrasonics for Imaging the Subsurface Defects.Sensors (Basel, Switzerland) · 2023Article
- Acoustic Velocity Measurement for Enhancing Laser UltraSound Imaging Based on Time Domain Synthetic Aperture Focusing Technique.Sensors (Basel, Switzerland) · 2023Article
- New "HOPE" laser for photoacoustic imaging of water.Light, science & applications · 2022Article
- Optoacoustic Sensing of Surfactant Crude Oil in Thermal Relaxation and Nonlinear Regimes.Sensors (Basel, Switzerland) · 2021Article
- Obstetric ultrasound: where are we and where are we going?Ultrasonography (Seoul, Korea) · 2021Article
- Biosensors Based on Mechanical and Electrical Detection Techniques.Sensors (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Full noncontact laser ultrasound (LUS) imaging has several distinct advantages over current medical ultrasound (US) technologies: elimination of the coupling mediums (gel/water), operator-independent image quality, improved repeatability, and volumetric imaging. Current light-based ultrasound utilizing tissue-penetrating photoacoustics (PA) generally uses traditional piezoelectric transducers in contact with the imaged tissue or carries an optical fiber detector close to the imaging site. Unlike PA, the LUS design presented here minimizes the optical penetration and specifically restricts optical-to-acoustic energy transduction at the tissue surface, maximizing the generated acoustic source amplitude. With an appropriate optical design and interferometry, any exposed tissue surfaces can become viable acoustic sources and detectors. LUS operates analogously to conventional ultrasound but uses light instead of piezoelectric elements. Here, we present full noncontact LUS results, imaging targets at ~5 cm depths and at a meter-scale standoff from the target surface. Experimental results demonstrating volumetric imaging and the first LUS images on humans are presented, all at eye- and skin-safe optical exposure levels. The progression of LUS imaging from tissue-mimicking phantoms, to excised animal tissue, to humans in vivo is shown, with validation from conventional ultrasound images. The LUS system design insights and results presented here inspire further LUS development and are a significant step toward the clinical implementation of LUS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.