Evidence map›Paper›PMID 31885827›Full record

ReviewOxidative medicine and cellular longevity2019

Advanced Glycation End Products: Potential Mechanism and Therapeutic Target in Cardiovascular Complications under Diabetes.

Ping Yang, Jian Feng, Qing Peng, Xing Liu, Zhongcai Fan

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dietary Advanced Glycation End Products and Cardiovascular-Kidney-Metabolic Complications.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  9. Article
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  12. Review
  13. Pasuchaca (Foods (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Black mulberry (Heliyon · 2025
    Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ping YangDepartment of Vasculocardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.
Jian FengDepartment of Vasculocardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.
Qing PengDepartment of Vasculocardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.
Xing LiuDepartment of Vasculocardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.
Zhongcai FanDepartment of Vasculocardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.ORCID https://orcid.org/0000-0003-0192-1146
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence and development of cardiovascular complications are predominantly responsible for the increased morbidity and mortality observed in patients with diabetes. Oxidative stress under hyperglycemia is currently considered the initial link to diabetic cardiovascular complications and a key node for the prevention and treatment of diabetes-related fatal cardiovascular events. Numerous studies have indicated that the common upstream pathway in the context of oxidative stress in the cardiovascular system under diabetic conditions is the interaction of advanced glycation end products (AGEs) with their receptors (RAGEs). Therefore, a further understanding of the relationship between oxidative stress and AGEs is of great significance for the prevention and treatment of cardiovascular complications in patients with diabetes. In this review, we will briefly summarize the recent research advances in diabetes with an emphasis on oxidative stress and its association with AGEs in diabetic cardiovascular complications.

Indexed as

AnimalsCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusGlycation End Products, AdvancedHumansHyperglycemiaOxidative StressReceptor for Advanced Glycation End ProductsSignal TransductionGlycation End Products, AdvancedReceptor for Advanced Glycation End Products

Identifiers

PMID31885827
PMCPMC6925928
OpenAlexW2992584895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.