Evidence map›Paper›PMID 31885814›Full record

ArticleOxidative medicine and cellular longevity2019

Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.

Yu Zhuang, Huirong Wu, Xiangxiang Wang, Jieyu He, Shanping He, Yulong Yin

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 2 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 2 syntheses or guidelines pooled it, 330 citations in OpenAlex.

  1. Pooled it
  2. Genetic polymorphisms and protein levels in vocal fold leukoplakia: a systematic review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Pooled it
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  17. Food science & nutrition · 2025
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119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yu ZhuangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.
Huirong WuHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.
Xiangxiang WangHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.ORCID https://orcid.org/0000-0002-8031-9657
Jieyu HeHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.ORCID https://orcid.org/0000-0001-8878-2390
Shanping HeHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.ORCID https://orcid.org/0000-0002-0065-4085
Yulong YinHunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, School of Life Sciences, Hunan Normal University, Changsha, 410081 Hunan, China.ORCID https://orcid.org/0000-0001-6112-6975
Hunan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is implicated in a wide range of intestinal disorders and closely associated with their pathological processes. Resveratrol (RSV), a plant extract, plays a vital role in protecting various organs

Indexed as

AnimalsAntioxidantsClaudin-1Gene Expression RegulationHEK293 CellsHumansHydrogen PeroxideIntestinal MucosaNF-E2-Related Factor 2Oncogene Protein v-aktOxidative StressPhosphatidylinositol 3-KinasesResveratrolRNA, Small InterferingSignal TransductionSwineAntioxidantsClaudin-1Hydrogen PeroxideNFE2L2 protein, humanNF-E2-Related Factor 2Oncogene Protein v-aktPhosphatidylinositol 3-KinasesResveratrolRNA, Small Interfering

Identifiers

PMID31885814
PMCPMC6915002
OpenAlexW2993445713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.