Evidence map›Paper›PMID 31885784›Full record

ArticleOxidative medicine and cellular longevity2019

Genipin Ameliorates Carbon Tetrachloride-Induced Liver Injury in Mice via the Concomitant Inhibition of Inflammation and Induction of Autophagy.

Ya Wang, Tianming Zhao, You Deng, Lijun Hou, Xiaofei Fan, Lin Lin, Wei Zhao, Kui Jiang, Chao Sun

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  4. Therapeutic potentials of iridoids derived from Rubiaceae against in vitro and in vivo inflammation: A scoping review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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  5. Article
  6. Article
  7. Review
  8. Andrographolide Suppresses Pyroptosis inOxidative medicine and cellular longevity · 2022
    Article
  9. Polydeoxyribonucleotide Exerts Protective Effect Against CClInternational journal of molecular sciences · 2020
    Article
  10. Review
  11. Qingxin Kaiqiao Fang Inhibits AEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ya WangDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0001-5375-3901
Tianming ZhaoDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0002-4909-7160
You DengDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0003-0393-1153
Lijun HouDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0002-7005-6937
Xiaofei FanDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0001-6273-3902
Lin LinDepartment of Gastroenterology, Tianjin Medical University General Hospital Airport Hospital, East Street 6, Tianjin Airport Economic Area, Tianjin 300308, China.ORCID https://orcid.org/0000-0002-2533-2103
Wei ZhaoDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0001-6707-7211
Kui JiangDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0002-5935-1409
Chao SunDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.ORCID https://orcid.org/0000-0002-0380-7999
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genipin, as the most effective ingredient of various traditional medications, encompasses antioxidative, anti-inflammatory, and antibacterial capacities. More recently, it is suggested that genipin protects against septic liver damage by restoring autophagy. The purpose of the current study was to explore the protective effect of genipin against carbon tetrachloride- (CCl

Indexed as

AnimalsAutophagyCarbon TetrachlorideChemical and Drug Induced Liver InjuryDisease Models, AnimalInflammationIridoidsLiverMaleMedicine, TraditionalMiceRubiaceaeCarbon TetrachloridegenipinIridoids

Identifiers

PMID31885784
PMCPMC6927019
OpenAlexW2996122225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.