Evidence map›Paper›PMID 31885773›Full record

ArticleOxidative medicine and cellular longevity2019

4-Hydroxychalcone Induces Cell Death via Oxidative Stress in

Amnah M Alshangiti, Eszter Tuboly, Shane V Hegarty, Cathal M McCarthy, Aideen M Sullivan, Gerard W O'Keeffe

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  5. Article
  6. Emerging therapeutic targets for neuroblastoma.Expert opinion on therapeutic targets · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Amnah M AlshangitiDepartment of Anatomy and Neuroscience, University College Cork, Cork, Ireland.ORCID https://orcid.org/0000-0002-3310-8523
Eszter TubolyDepartment of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.
Shane V HegartyDepartment of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
Cathal M McCarthyDepartment of Pharmacology and Therapeutics, University College Cork, Cork, Ireland.
Aideen M SullivanDepartment of Anatomy and Neuroscience, University College Cork, Cork, Ireland.ORCID https://orcid.org/0000-0001-9692-6438
Gerard W O'KeeffeDepartment of Anatomy and Neuroscience, University College Cork, Cork, Ireland.ORCID https://orcid.org/0000-0001-5149-0933
University College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is an embryonal malignancy that arises from cells of sympathoadrenal lineage during the development of the nervous system. It is the most common pediatric extracranial solid tumor and is responsible for 15% of childhood deaths from cancer. Fifty percent of cases are diagnosed as high-risk metastatic disease with a low overall 5-year survival rate. More than half of patients experience disease recurrence that can be refractory to treatment. Amplification of the

Indexed as

Cell DeathCell Line, TumorChalconesHumansNeuroblastomaN-Myc Proto-Oncogene ProteinOxidative StressChalconesN-Myc Proto-Oncogene Protein

Identifiers

PMID31885773
PMCPMC6915131
OpenAlexW2992011739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.