Evidence map›Paper›PMID 31885770›Full record

ArticleOxidative medicine and cellular longevity2019

Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena.

Xiaoran Huang, Hao Zhang, Xiaoting Liang, Yimei Hong, Mengmeng Mao, Qian Han, Haiwei He, Wuyuan Tao, Guojun Jiang, Yuelin Zhang and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

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  8. Novel pharmacological approaches in abdominal aortic aneurysm.Clinical science (London, England : 1979) · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Editorial: Mesenchymal Stem Cell Senescence and Rejuvenation.Frontiers in cell and developmental biology · 2021
    Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Xiaoran HuangMedical College, Shantou University, Shantou, Guangdong, China.
Hao ZhangSchool of Pharmacy, Bengbu Medical College, Bengbu, Anhui, China.
Xiaoting LiangClinical Translational Medical Research Centre, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yimei HongDepartment of Emergency Medicine, Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Mengmeng MaoDepartment of Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China.
Qian HanDepartment of Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China.
Haiwei HeDepartment of Emergency Medicine, Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Wuyuan TaoDepartment of Emergency Medicine, Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Guojun JiangSchool of Pharmacy, Bengbu Medical College, Bengbu, Anhui, China.
Yuelin ZhangDepartment of Emergency Medicine, Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-0065-1116
Xin LiDepartment of Emergency Medicine, Department of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-0469-5121
Guangdong Academy of Medical Sciences · CNBengbu Medical College · CNFirst Affiliated Hospital of Guangzhou Medical University · CNShantou University · CNShanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) have shown beneficial effects in the treatment of abdominal aortic aneurysm (AAA). Nonetheless, the biological properties of adipose-derived MSCs (ASCs) from patients with AAA (AAA-ASCs) remain unclear. This study is aimed at investigating the properties of cell phenotype and function of AAA-ASCs compared with ASCs from age-matched healthy donors (H-ASCs). H-ASCs and AAA-ASCs were studied for cell phenotype, differentiation capacity, senescence, and mitochondrial and autophagic functions. Cellular senescence was examined by senescence-associated

Indexed as

Cellular SenescenceAdipose TissueAgedAortic Aneurysm, AbdominalAutophagyCase-Control StudiesCell MovementCell ProliferationDNA DamageFemaleHumansMaleMembrane Potential, MitochondrialMesenchymal Stem CellsMicrotubule-Associated ProteinsMiddle AgedMicrotubule-Associated ProteinsReactive Oxygen Species

Identifiers

PMID31885770
PMCPMC6899325
OpenAlexW2990846129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.