ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2019
Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection.
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The correlation between vaginal pathogens and high-risk human papilloma virus infection: a meta-analysis of case-control studies.Frontiers in oncology · 2024Pooled it
- Bacterial vaginosis and cervical human papillomavirus infection in young and adult women: a systematic review and meta-analysis.Revista de saude publica · 2023Pooled it
- Vaginal Microbiota and Local Immunity in HPV-Induced High-Grade Cervical Dysplasia: A Narrative Review.International journal of molecular sciences · 2025Review
- Prevalence ofTropical medicine and infectious disease · 2025Review
- Molecular Detection of Human Papillomavirus (HPV) and Other Sexually Transmitted Pathogens in Cervical and Self-Collected Specimens.International journal of molecular sciences · 2025Article
- Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor.Microbial cell factories · 2025Article
- High frequency of sexually transmitted infections in patients with precancerous cervical lesions in Brazil.Frontiers in public health · 2025Article
- Advances in the interrelated nature of vaginal microecology, HPV infection, and cervical lesions.Frontiers in cellular and infection microbiology · 2025Review
- Could APTIMA mRNA Assay Contribute to Predicting Cervical Bacterial Sexually Transmitted Co-Infections? A Colposcopy Population Study.International journal of molecular sciences · 2024Article
- Article
- Clinical and uterine cervix characteristics of women with Mycoplasma and Ureaplasma in genital discharge.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Cervical HPV Infections, Sexually Transmitted Bacterial Pathogens and Cytology Findings-A Molecular Epidemiology Study.Pathogens (Basel, Switzerland) · 2023Article
- Vaginal and tumor microbiomes in gynecological cancer (Review).Oncology letters · 2023Review
- Analyses of human papillomavirus, Chlamydia trachomatis, Ureaplasma urealyticum, Neisseria gonorrhoeae, and co-infections in a gynecology outpatient clinic in Haikou area, China.BMC women's health · 2023Article
- The correlation between Trichomonas vaginalis infection and reproductive system cancer: a systematic review and meta-analysis.Infectious agents and cancer · 2023Article
- Article
- Prevalence of Precancerous Cervical Lesions among Nonvaccinated Kazakhstani Women: The National Tertiary Care Hospital Screening Data (2018).Healthcare (Basel, Switzerland) · 2023Article
- The Immunomodulation Role of Vaginal Microenvironment On Human Papillomavirus Infection.Galen medical journal · 2023Article
- Meta-analysis of the correlation between vaginal microenvironment and HPV infection.American journal of translational research · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-risk human papillomavirus (hr-HPV) infection is a necessary cause of cervical cancer. However, other common lower genital tract microbes may increase hr-HPV infection and their related cervical cytopathy.
methodsTo confirm this hypothesis, cervical brush and vaginal swab specimens were collected from 826 adult patients who were divided into the hr-HPV-positive group (254) and the negative group (572) by real-time PCR assay. Cervical specimens were tested for
resultsAmong hr-HPV-positive women, UP was found in 51.6%, UU in 15.4%, CT in 15.7%,
conclusionThese microbes might induce cervical chronic inflammation that would damage the mucosal barrier and immune protection to promote the infection of hr-HPV.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.