Evidence map›Paper›PMID 31885709›Full record

ArticleExperimental and therapeutic medicine2020

A novel approach regarding the anti-aging of facial skin through collagen reorganization.

Maria Sifaki, Daniela Calina, Anca Oana Docea, Sotiris Tsioumas, Martha-Spyridoula Katsarou, Sevasti Papadogiorgaki, Persefoni Fragkiadaki, Daciana Elena Branisteanu, Konstantinos Kouskoukis, John Tsiaoussis and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. The role of selected flavonoids from bajakah tampala (Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  2. Review
  3. Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  4. Article
  5. Tobacco Smoking and LiverJournal of oncology · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Maria SifakiPrivate Practice Dermatologist-Venereologist, 71305 Heraklion, Greece.
Daniela CalinaDepartment of Clinical Pharmacy, Dermatopharmacy and Cosmetology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Sotiris TsioumasPrivate Practice Ophthalmologist, 11528 Athens, Greece.
Martha-Spyridoula KatsarouResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Sevasti PapadogiorgakiTeaching and Technical Support Staff, Laboratory of Electron Microscope, Medical School, University of Crete, 71003 Heraklion, Greece.
Persefoni FragkiadakiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Daciana Elena BranisteanuDepartment of Dermatology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.
Konstantinos KouskoukisDepartment of Dermatology and Venereology, Medical School, Democritus University of Thrace, 68100 Alexandroupoli, Greece.
John TsiaoussisLaboratory of Anatomy-Histology-Embryology, Medical School, University of Crete, 71003 Heraklion, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
University of Crete · GRUniversity of Medicine and Pharmacy of Craiova · RODemocritus University of Thrace · GRGrigore T. Popa University of Medicine and Pharmacy · RONational and Kapodistrian University of Athens · GRThe General Hospital of Heraklion "Venizeleio-Pananio" · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The needle shaping technique can be used to perform subcutaneous microtransplants, enabling the 'lifting' of the skin. This prospective cohort study aimed to examine the effects of needle shaping on facial skin tone, volume and histological structure. A total of 54 women underwent the needle shaping procedure performed by inserting a tiny acupuncture needle combined with mixed electrical currents. The overall treatment was completed within 4 sessions of 2 months apart, once every 15 days. Maintenance was ensured by 2 sessions (no longer than 15 days apart) every 6 months. Macroscopic skin appearance was evaluated by a specialized dermatologist and the satisfaction of the patients was assessed. The microscopic structure of the skin dermis was evaluated by optic and scanning electron microscopy. I-chrome staining demonstrated more compact dermis-collagen fibers which were larger and thicker as compared to the controls. Scanning electron microscopy demonstrated an increased dermis thickness as compared to pre-treatment. All patients that answered to the follow up reported satisfaction during assessment. The satisfaction of the patients was very good and excellent in 45% of cases. The results of the needle-shaping procedure are natural with no scaring or down time. Moreover, the result is lasting even for 1 year, depending always on the subject's lifestyle and general health condition.

Indexed as

anti-aging effectcollagen reorganizationfacial skinneedle shapingnew collagen synthesis

Identifiers

PMID31885709
PMCPMC6913239
OpenAlexW2989696559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.