Evidence map›Paper›PMID 31885616›Full record

ArticleStem cells international2019

Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation.

Marco Viganò, Gaia Lugano, Carlotta Perucca Orfei, Alessandra Menon, Enrico Ragni, Alessandra Colombini, Paola De Luca, Pietro Randelli, Laura de Girolamo

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marco ViganòOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID https://orcid.org/0000-0002-6463-6564
Gaia LuganoOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Carlotta Perucca OrfeiOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID https://orcid.org/0000-0001-6162-8668
Alessandra MenonLaboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.ORCID https://orcid.org/0000-0003-2786-8099
Enrico RagniOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Alessandra ColombiniOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Paola De LucaOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Pietro RandelliLaboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.ORCID https://orcid.org/0000-0001-9331-820X
Laura de GirolamoOrthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID https://orcid.org/0000-0002-9979-3092
Istituto Ortopedico Galeazzi · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMesenchymal stem cells (MSCs) emerged as a promising therapy for tendon pathologies. Microfragmented adipose tissue (

methodsCell viability and proliferation were evaluated after 48 hours of transwell coculture of TCs and autologous

resultsIL-1

conclusionsIn this in vitro model of tendon cell inflammation, the paracrine action of

Identifiers

PMID31885616
PMCPMC6915130
OpenAlexW2993107809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.