Evidence map›Paper›PMID 31885599›Full record

ArticleCase reports in medicine2019

Spirochetes in the Liver: An Unusual Presentation of a Common STI.

Natasha Narang, Layth Al-Jashaami, Nayan Patel

Abstract readCase Reports
In one paragraph

Article in Case reports in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Intrahepatic cholestasis due to Treponema pallidum in an immunocompetent patientBiomedica : revista del Instituto Nacional de Salud · 2023
    Article
  2. Autoimmune Hepatitis Induced after Treatment of Syphilitic Hepatitis.Journal of clinical and translational hepatology · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natasha NarangDepartment of Internal Medicine, Banner University Medical Center, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0002-8740-5929
Layth Al-JashaamiDepartment of Gastroenterology, Banner University Medical Center, Phoenix, AZ, USA.
Nayan PatelDepartment of Gastroenterology, Banner University Medical Center, Phoenix, AZ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is estimated that 10% of patients with secondary syphilis have liver enzyme elevations, but clinical hepatitis is rare. However, in HIV-positive patients, syphilitic hepatitis may be much more common. We report a case of a 67-year-old male who developed progressively elevated liver enzymes, followed by development of neurological symptoms and then rash. Though the timeline of his symptom development was unusual, his constellation of symptoms prompted an RPR and FTA-ABS which returned reactive. He was additionally found to be HIV positive with a CD4 count of 946. He was treated with IV Penicillin, and his hepatitis improved thereafter.

Identifiers

PMID31885599
PMCPMC6927064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.