Evidence map›Paper›PMID 31885529›Full record

ArticleAdvanced functional materials2019

Molecular imaging in the second near-infrared window.

Hao Wan, Haotian Du, Feifei Wang, Hongjie Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao WanDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Haotian DuDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Feifei WangDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Hongjie DaiDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.

Funding

Human Infrared Vision at Molecular and Cellular ScaleDP1NS105737 · NINDS · STANFORD UNIVERSITY · PI DAI, HONGJIE · 2017 to 2022
$5.5M
NINDS NIH HHS DP1 NS105737
6 · The paper itself

Abstract

In the past decade, noticeable progress has been achieved regarding fluorescence imaging in the second near-infrared (NIR-II) window. Fluorescence imaging in the NIR-II window demonstrates superiorities of deep tissue penetration and high spatial and temporal resolution, which are beneficial for profiling physiological processes. Meanwhile, molecular imaging has emerged as an efficient tool to decipher biological activities on the molecular and cellular level. Extending molecular imaging into the NIR-II window would enhance the imaging performance, providing more detailed and accurate information of the biological system. In this progress report, selected achievements made in NIR-II molecular imaging are summarized. The organization of this report is based on strategies underlying rational designs of NIR-II imaging probes and their applications in molecular imaging are highlighted. This progress report may provide guidance and reference for further development of functional NIR-II probes designed for high-performance molecular imaging.

Indexed as

molecular imagingNIR-II window

Identifiers

PMID31885529
PMCPMC6934177

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.