SynthesisWorld journal of gastroenterology2019
Epidemiology of inflammatory bowel disease in South America: A systematic review.
Synthesis in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Colonoscopy-guided therapy for the prevention of post-operative recurrence of Crohn's disease.The Cochrane database of systematic reviews · 2020Pooled it
- Design, Synthesis, and Structure-Activity Relationships of Substituted Phenyl Cyclobutylureas as Potential Modulators of Inflammatory Responses.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Hospitalization rate for ulcerative colitis and Crohn's disease in Brazil and its correlation with socioeconomic inequalities.BMC gastroenterology · 2026Article
- Article
- QuYuShengXin formula reshapes bile-acid-mediated macrophage polarization in the treatment of ulcerative colitis.BMC complementary medicine and therapies · 2025Article
- Bidirectional Interplay Between IBD Therapies and the Gut Microbiota: A Pharmacomicrobiomic Approach to Personalized Treatment.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025Review
- Global Inflammatory Bowel Disease: Opportunities and Challenges for a New Era.United European gastroenterology journal · 2025Review
- Observing the Influence of Shame and Guilt in Inflammatory Bowel Disease: A Systematic Review.Clinical neuropsychiatry · 2025Review
- Imaging characteristics of brain microstructure and cerebral perfusion in Crohn's disease patients with anxiety: A prospective comparative study.World journal of gastroenterology · 2025Article
- Differential analysis of sorting nexin 10 and sterol regulatory element-binding protein 2 expression in inflammatory bowel disease.Immunologic research · 2024Article
- The Role of Gut Microbiome in the Pathogenesis and the Treatment of Inflammatory Bowel Diseases.Cureus · 2024Review
- Food-Related Quality of Life Is Impaired in Latinx and Non-Latinx Patients With Inflammatory Bowel Disease.Gastro hep advances · 2024Article
- IBD barriers across the continents: a continent-specific analysis: Latin America.Therapeutic advances in gastroenterology · 2023Review
- ASSESSMENT OF RISK FACTORS FOR SURGERY TREATMENT OF CROHN'S DISEASE: A HOSPITAL COHORT.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023Article
- A Multicentre Study of the Clinical and Epidemiological Profile of Inflammatory Bowel Disease in Northeast Brazil.Clinical and experimental gastroenterology · 2023Article
- Comprehensive Phenotyping in Inflammatory Bowel Disease: Search for Biomarker Algorithms in the Transkingdom Interactions Context.Microorganisms · 2022Article
- Colorectal Surgery Practice, Training, and Research in Low-Resource Settings.Clinics in colon and rectal surgery · 2022Review
- Epidemiology of inflammatory bowel diseases in the state of Rio Grande do Sul, Brazil.World journal of gastroenterology · 2022Observational
- Article
- Yiyi Fuzi Baijiang Decoction Alleviates Ulcerative Colitis Partly by Regulating TLR4-Mediated PI3K/Akt and NF-Evidence-based complementary and alternative medicine : eCAM · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe worldwide epidemiology of inflammatory bowel disease (IBD) is rapidly changing. Increasing Crohn's disease (CD) and ulcerative colitis (UC) incidence and prevalence have been recorded in developing regions such as Asia, Africa and Eastern Europe where it was previously thought to be uncommon. Whether this is also the case in South America is not well known. Demonstration that developing regions worldwide have increasing IBD incidence would indicate that environmental change plays a significant role in the development of IBD.
aimTo report the incidence, prevalence and disease characteristics of CD and UC within the South American continent.
methodsA systematic review was conducted by searching published studies in major international and regional databases (MEDLINE, EMBASE and Scopus) between January 1990 and December 2018. Outcomes considered were incidence, prevalence, phenotype, environmental and genetic factors, ethnicity and gender. A pair of independent reviewers screened and reviewed all identified articles.
resultsOne hundred and sixty two citations were initially retrieved with 18 studies included in this systematic review. The majority of included studies were from Brazil (
conclusionThe IBD burden in South America is increasing at a rate possibly even greater than other developing regions around the world. There is a paucity of high-quality epidemiological studies and further robust and representative data are required to further explore modifiable risk factors and disease phenotypes.
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