Evidence map›Paper›PMID 31885050›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2020

Geospatial analysis of dengue emergence in rural areas in the Southern Province of Sri Lanka.

Charmaine P Mutucumarana, Champica K Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, Ruvini Kurukulasooriya, Thamali Anuradha, Aruna Dharshan De Silva, Mark M Janko, Truls Østbye, Duane J Gubler and 4 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Observational
  7. Rising trend of dengue in urban areas: A challenge.Journal of family medicine and primary care · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Charmaine P MutucumaranaDuke University School of Medicine, Durham, NC 27710, USA.
Champica K BodinayakeDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Ajith NagahawatteDepartment of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Vasantha DevasiriDepartment of Pediatrics, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Ruvini KurukulasooriyaDuke Ruhuna Collaborative Research Center, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Thamali AnuradhaDuke Ruhuna Collaborative Research Center, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Aruna Dharshan De SilvaFaculty of Medicine, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.
Mark M JankoDuke Global Health Institute, Durham, NC 27710, USA.
Truls ØstbyeDuke Global Health Institute, Durham, NC 27710, USA.
Duane J GublerDuke Global Health Institute, Durham, NC 27710, USA.
Christopher W WoodsDuke Global Health Institute, Durham, NC 27710, USA.
Megan E RellerDuke Global Health Institute, Durham, NC 27710, USA.
L Gayani TillekeratneDuke Global Health Institute, Durham, NC 27710, USA.
Paul M LantosDuke Global Health Institute, Durham, NC 27710, USA.
Duke Institute for Health Innovation · USUniversity of Ruhuna · LKDuke University · USGeneral Sir John Kotelawala Defence University · LK

Funding

Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited SettingsK23AI125677 · NIAID · DUKE UNIVERSITY · PI TILLEKERATNE, GAYANI · 2017 to 2021
$905k
Reducing morbidity and mortality from acute febrile illness by improved diagnosisK23AI083931 · NIAID · JOHNS HOPKINS UNIVERSITY · PI RELLER, MEGAN ELIZABETH · 2010 to 2012
$407k
FIC NIH HHS R25 TW009337NIAID NIH HHS K23 AI083931NIAID NIH HHS K23 AI125677
6 · The paper itself

Abstract

backgroundDengue is a major cause of acute febrile illness in Sri Lanka. Dengue has historically been considered an urban disease. In 2012-2013, we documented that acute dengue was surprisingly associated with self-reported rural residence in the Southern Province of Sri Lanka.

methodsPatients admitted with an acute febrile illness were enrolled from June 2012-May 2013 in a cross-sectional surveillance study at the largest tertiary care hospital in the Southern Province. Acute dengue was diagnosed by serology and virology testing. Site visits were performed to collect residential geographical coordinates. Spatial variation in odds of acute dengue was modeled using a spatial generalized additive model predicted onto a grid of coordinate pairs covering the Southern Province.

resultsOf 800 patients, 333 (41.6%) had laboratory-confirmed acute dengue. Dengue was spatially heterogeneous (local probability of acute dengue 0.26 to 0.42). There were higher than average odds of acute dengue in the rural northeast of the Southern Province and lower than average odds in the urbanized southwest of the Southern Province, including the city Galle.

conclusionsOur study further affirms the emergence of dengue in rural southern Sri Lanka and highlights both the need for real-time geospatial analyses to optimize public health activities as well as the importance of strengthening dengue surveillance in non-urban areas.

Indexed as

DengueCross-Sectional StudiesFeverHumansPublic HealthSri LankadenguefeverprobabilitySri Lankaurbanization

Identifiers

PMID31885050
PMCPMC7528758
OpenAlexW2998463117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.