Evidence map›Paper›PMID 31884976›Full record

ArticleEpidemiology and infection2019

Seasonality of the transmissibility of hand, foot and mouth disease: a modelling study in Xiamen City, China.

Zehong Huang, Mingzhai Wang, Luxia Qiu, Ning Wang, Zeyu Zhao, Jia Rui, Yao Wang, Xingchun Liu, Mikah Ngwanguong Hannah, Benhua Zhao and 3 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  16. Control measures during the COVID-19 outbreak reduced the transmission of hand, foot, and mouth disease.Journal of safety science and resilience = An quan ke xue yu ren xing (Ying wen) · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zehong HuangState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Mingzhai WangXiamen Centre for Disease Control and Prevention, Xiamen City, Fujian Province, People's Republic of China.
Luxia QiuState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Ning WangRespiratory Department, Shanghai General Hospital, Shanghai, People's Republic of China.
Zeyu ZhaoState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Jia RuiState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Yao WangState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Xingchun LiuState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Mikah Ngwanguong HannahMedical College, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.ORCID 0000-0002-1494-7700
Benhua ZhaoState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Yanhua SuState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Bin ZhaoState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Laboratory Department, Xiang'an Hospital of Xiamen University, Xiamen City, Fujian Province, People's Republic of China.
Tianmu ChenState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.ORCID 0000-0003-0710-5086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study attempts to figure out the seasonality of the transmissibility of hand, foot and mouth disease (HFMD). A mathematical model was established to calculate the transmissibility based on the reported data for HFMD in Xiamen City, China from 2014 to 2018. The transmissibility was measured by effective reproduction number (Reff) in order to evaluate the seasonal characteristics of HFMD. A total of 43 659 HFMD cases were reported in Xiamen, for the period 2014 to 2018. The median of annual incidence was 221.87 per 100 000 persons (range: 167.98/100,000-283.34/100 000). The reported data had a great fitting effect with the model (R2 = 0.9212, P < 0.0001), it has been shown that there are two epidemic peaks of HFMD in Xiamen every year. Both incidence and effective reproduction number had seasonal characteristics. The peak of incidence, 1-2 months later than the effective reproduction number, occurred in Summer and Autumn, that is, June and October each year. Both the incidence and transmissibility of HFMD have obvious seasonal characteristics, and two annual epidemic peaks as well. The peak of incidence is 1-2 months later than Reff.

Indexed as

Models, BiologicalSeasonsChinaComputer SimulationHand, Foot and Mouth DiseaseHumansIncidenceReproducibility of ResultsEffective reproduction numberhand, foot and mouth diseaseseasonalitytransmissibility

Identifiers

PMID31884976
PMCPMC7006018

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.